Protein Alignment Hsc70Cb and hspa8b

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 690
• Identity: 188/690 - (27%)
• Similarity: 334/690 - (48%)
• Gaps: 101/690 - (14%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            :|||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|..|||...|
Zfish     7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPTNTVFDAK 71

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:||:|:|..||.::...|..| ...:....::|.|.||.:.|.||::::|:.||:||.:.|.:
Zfish    72 RLIGRRFDDAVVQSDMKHWPFTV-INDNLRPKVQVEYKGETKTFYPEEVSSMVLTKMKEIAEAYL 135

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            ...:.:.||..|.:|.:::|:|..||..|:||||||::||.||.|:|||..|.   ....|||:.
Zfish   136 GKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKK---VGSERNVLI 197

  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANLR 262
            .|.|..:...|......|..::.::..| .:||.|.|..:..:|..||:.:||.:...|.||..|
Zfish   198 FDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDISDNKRAVRR 262

  Fly   263 LLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKL 327
            |.|..|:.|:.:| :||:..:.|:...:.||..:|:.|::.|||.|.:.:......::.|.::||
Zfish   263 LRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKL 326

  Fly   328 QLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIM--SPAVRVREF 389
            ....:|.:.:||||:|||.:::|::..|| |..:.::|.||||:.|||:|.||:  ..:..|::.
Zfish   327 DKSQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQDL 391

  Fly   390 GVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHAS-PFSRLLTI-----NRKGPFNVSIVYGQQVP 448
            .:.|:...::.:      ..|.|.:.|..:.:.: |..:..|.     |:.|.. :.:..|::..
Zfish   392 LLLDVTPLSLGI------ETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVL-IQVYEGERAM 449

  Fly   449 YPDQT-IGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEE 512
            ..|.. :|.:::..:.|..||..| :::...|:.|||:.:|               |.:::..:|
Zfish   450 TKDNNLLGKFELTGIPPAPRGVPQ-IEVTFDIDANGIMNVS---------------AVDKSTGKE 498

  Fly   513 KPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELP 577
            .....||:.|.
Zfish   499 NKITITNDKGR------------------------------------------------------ 509

  Fly   578 LECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAER 642
                   .|..|:....|:..|....|..:.|::.|||.||.:.::|::.::....:..:.|.::
Zfish   510 -------LSKEDIERMVQEAEKYKAEDDVQREKVSAKNGLESYSFNMKSTVEDEKLKGKISEEDK 567

  Fly   643 EKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPI 682
            :||:::.|::.:|| :..:..|::.:..:.:.|.:..:||
Zfish   568 QKIINKCNEVISWL-DKNQTAEKEEFEHQQKELEKLCNPI 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	140/380 (37%)
		HSP70	3..682	CDD:278441	186/688 (27%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	188/690 (27%)
		HSPA1-2_6-8-like_NBD	6..380	CDD:212675	139/377 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740