Protein Alignment Hsc70Cb and Hsc70-2

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 709
• Identity: 200/709 - (28%)
• Similarity: 346/709 - (48%)
• Gaps: 113/709 - (15%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            ||||.|.....|...::..:|.:|||...|.|||:|||:..:|:||..||||...|.||||...|
  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAK 71

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:||||:|..:|.:|...|.:| ....|...|:|.:.||.:.|.||::::|:.||::|.:...:
  Fly    72 RLIGRKFDDKKIQEDLKLWPFKV-INEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            ..:|.|.|:..|.:|.:::|:|..||..||||||||::||.||.|||||..||...|   |||:.
  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGE---RNVLI 197

  Fly   199 VDFGHSSLQASACAFTKGKL-KMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANL 261
            .|.|..:...|..:..:|.| ::.|:..| .:||.|.|..|.::||:||:.::|.:.|.||||..
  Fly   198 FDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALR 262

  Fly   262 RLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESK 326
            ||.|..|:.|:.:| :||:..|.|:...:.||..|.:.|::.|||...:.:...|..:|.|:::|
  Fly   263 RLRTACERAKRTLS-SSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAK 326

  Fly   327 LQLDDIHSVEIVGGSSRIPSVKQLIEQVF-NKPASTTLNQDEAVSRGAALQCAIMS--PAVRVRE 388
            :....||.|.:||||:|||.:::|::.:| .|..:.::|.||||:.|||:|.||::  .:.::::
  Fly   327 MDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQD 391

  Fly   389 FGVTDIQNYAVKVLWDSEGSAAPGEIE-----------IFPQYHASPFSRLLTINRKGPFNVSIV 442
            ..:.|:...::.:  ::.|......:|           ||..|.          :.:....:.:.
  Fly   392 LLLVDVAPLSLGI--ETAGGVMTNLVERNARIPCKQQQIFTTYS----------DNQNAVTIQVY 444

  Fly   443 YGQQVPYPDQT-IGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAE 506
            .|::....|.. :|.:.:..:.|..||..| :::...:|.:||:.:
  Fly   445 EGERAMTKDNNLLGTFNLTGIPPAPRGVPQ-IEVAFDLNADGILNV------------------- 489

  Fly   507 QAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKAS 571
                                        |..||:|         |.::::     :.::.|.:.|
  Fly   490 ----------------------------NAKDNST---------GKSEKI-----TISNDKGRLS 512

  Fly   572 KATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERY 636
            ||               ::.....:..|....|.::.||:.:||.||.::|..|..:...| ...
  Fly   513 KA---------------EIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGV 561

  Fly   637 VVEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAA 695
            :.|.||.|:..:.:...:|| :.....|::.:.|.|:...:...||..:....::|.::
  Fly   562 LSETERSKVRDKCSSEASWL-DKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSS 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	152/379 (40%)
		HSP70	3..682	CDD:278441	197/694 (28%)
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	200/709 (28%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	152/379 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740