Protein Alignment Hsc70Cb and hsc70

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Alignment Length: 691
• Identity: 192/691 - (27%)
• Similarity: 339/691 - (49%)
• Gaps: 103/691 - (14%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            :|||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|..|||...|
Zfish     7 VGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSNTVFDAK 71

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGS-IGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAA 132
            ||:||:|:||.||.::...|.:|.:  ||| ..::|.|.||.:.|.||::::|:.||:||.|.|.
Zfish    72 RLIGRRFDDPVVQSDMKHWPFKVIS--DGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEISEAY 134

  Fly   133 MQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVI 197
            :...|::.||..|.:|.:::|:|..||..||||||||::||.||.|:|||..|....|   |||:
Zfish   135 LGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGE---RNVL 196

  Fly   198 FVDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANL 261
            ..|.|..:...|......|..::.::..| .:||.|.|..:.::|..||:.::|.:...|.||..
Zfish   197 IFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVR 261

  Fly   262 RLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESK 326
            ||.|..|:.|:.:| :||:..:.|:...:..|..:|:.|::.|||.|.:.:...:..::.|.::|
Zfish   262 RLRTACERAKRTLS-SSTQASIEIDSLYEGADFYTSITRARFEELNADLFRGTLEPVEKALRDAK 325

  Fly   327 LQLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIMS--PAVRVRE 388
            :....||.:.:||||:|||.:::|::..|| :..:.::|.||||:.|||:|.||::  .:..|::
Zfish   326 MDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQD 390

  Fly   389 FGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHAS-PFSRLLTI-----NRKGPFNVSIVYGQQV 447
            ..:.|:...::.:      ..|.|.:.:..:.:.: |..:..|.     |:.|.. :.:..|::.
Zfish   391 LLLLDVTPLSLGI------ETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVL-IQVYEGERA 448

  Fly   448 PYPDQTI-GVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASE 511
            ...|..| |.:::..:.|..||..| :::...|:.|||:.:|               |.:::..:
Zfish   449 MTKDNNILGKFELTGIPPAPRGVPQ-IEVTFDIDANGILNVS---------------AVDKSTGK 497

  Fly   512 EKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATEL 576
            |.....||:.|.
Zfish   498 ENKITITNDKGR----------------------------------------------------- 509

  Fly   577 PLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAE 641
                    .|..|:....|:..:....|:.:.|::.|||.||...::|::.::....:..:...:
Zfish   510 --------LSKEDIERMVQEADQYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPED 566

  Fly   642 REKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPI 682
            ::.|..:.|::.:|| :..:..|:|.|..:.:.|.:..:||
Zfish   567 KKTITDKCNEVISWL-DKNQTAEKDEYEHQQKELEKVCNPI 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	145/379 (38%)
		HSP70	3..682	CDD:278441	190/689 (28%)
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	192/691 (28%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	145/379 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592206
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740