Protein Alignment Hsc70Cb and hspa9

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_958483.2
• Gene: hspa9 / 373085
• ZFINID: ZDB-GENE-030828-12
• Length: 682
• Species: Danio rerio
• Alignment Length: 702
• Identity: 185/702 - (26%)
• Similarity: 313/702 - (44%)
• Gaps: 141/702 - (20%)

  Fly     2 SVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAF--DGKKRIIGVAAKNQQVTNMKNTV 64
            :|||||.|..:..||.......:.|.|....|.|||.|||  || :|::|:.||.|.|||..||:
Zfish    57 AVIGIDLGTTNSCVAVMDGKNAKVLENAEGARTTPSVVAFTSDG-ERLVGMPAKRQAVTNPNNTL 120

  Fly    65 GGFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETS 129
            ...|||:||:|:|..||.:|.::|.::....:|...::|:    .:.:.|.|..|.:..|:|||:
Zfish   121 YATKRLIGRRFDDAEVQKDLKNVPYKIVRASNGDAWLEVH----GKMYSPSQAGAFILIKMKETA 181

  Fly   130 AAAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPR 194
            .:.:...|.:.|:..|.:|.:::|:|..||.|||||||||::||.||.|||||.   |..:||
Zfish   182 ESYLGQSVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGL---DKTQDK-- 241

  Fly   195 NVIFV-DFGHSSLQASACAFTKGKLKMLASTWDQ-IGGRDIDLALGDYFAKEFQERYKINAKTNA 257
             :|.| |.|..:...|.....||..::.::..|. :||.|.|..|..:..|||::...::...:.
Zfish   242 -IIAVYDLGGGTFDISVLEIQKGVFEVKSTNGDTFLGGEDFDQHLLRHIVKEFKKESGVDLMKDN 305

  Fly   258 RANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDID----VSSSMQRSQMEELCAPVLQRVEQTF 318
            .|..|:....||.|.::| :|.:..:|:.....|..    ::..:.|||.|.:.|.:::|.....
Zfish   306 MALQRVREAAEKAKCELS-SSLQTDINLPYLTMDASGPKHLNMKLTRSQFEGIVADLIRRTVAPC 369

  Fly   319 KRLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPA 383
            ::.:.::::...||..|.:|||.:|:|.|:|.::.:|.:..|.::|.||||:.|||:|..:::.
Zfish   370 QKAMQDAEVSKSDIGEVLLVGGMTRMPKVQQTVQDLFGRAPSKSVNPDEAVAIGAAIQGGVLAG- 433

  Fly   384 VRVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVY----- 443
                  .|||:....|..|  |.|....|.:          |::|:..|...|...|.|:
Zfish   434 ------DVTDVLLLDVTPL--SLGIETLGGV----------FTKLINRNTTIPTKKSQVFSTAAD 480

  Fly   444 GQ------------QVPYPDQTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKK 496
            ||            ::...::.:|.:.:..:.|..||..| :::...|:.||||.:|
Zfish   481 GQTQVEIKVCQGEREMATDNKVLGQFTLVGIPPALRGVPQ-IEVTFDIDANGIVHVS-------- 536

  Fly   497 EAEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFG 561
             |::.....||....:..|
Zfish   537 -AKDKGTGREQQIVIQSSG---------------------------------------------- 554

  Fly   562 SGADKKKKASKATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRN 626
                                  |.|..|:.|..:...|....|::..:|::|.|..|..|:|..:
Zfish   555 ----------------------GLSKDDIENMVKNAEKYAEEDRRRKDRVEAVNMAEGIVHDTES 597

  Fly   627 KLQGGPFERYVVEAEREKIVSQLNDLENWL----YEDGEDCERDIYTSRLQA 674
            |::  .|:..:...|..|:..:::.:...|    .|.||:. :...||..||
Zfish   598 KME--EFKDQLPADECNKLKEEISKVRELLSRKDTETGENI-KQAATSLQQA 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	130/386 (34%)
		HSP70	3..682	CDD:278441	185/701 (26%)
hspa9	NP_958483.2	HSPA9-like_NBD	55..431	CDD:212683	130/385 (34%)
		dnaK	56..659	CDD:234715	185/702 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900