Protein Alignment Hsc70Cb and hsp-6

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_001370558.1
• Gene: hsp-6 / 178873
• WormBaseID: WBGene00002010
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 727
• Identity: 190/727 - (26%)
• Similarity: 315/727 - (43%)
• Gaps: 147/727 - (20%)

  Fly     3 VIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAF--DGKKRIIGVAAKNQQVTNMKNTVG 65
            |||||.|..:..|:.......:.:.|...:|.|||.|||  || :|::|..||.|.|||..||:.
 Worm    33 VIGIDLGTTNSCVSIMEGKTPKVIENAEGVRTTPSTVAFTADG-ERLVGAPAKRQAVTNSANTLF 96

  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130
            ..|||:||::.||.||.:|..:|.::....:|...::    .:.:.:.|.|:.|.:..|:|||:.
 Worm    97 ATKRLIGRRYEDPEVQKDLKVVPYKIVKASNGDAWVE----AQGKVYSPSQVGAFVLMKMKETAE 157

  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRN 195
            :.:.|.||:.|:..|.:|.:::|:|..||.||:||||||::||.||.|||||     |.:|....
 Worm   158 SYLGTTVNNAVVTVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYG-----LDKDAGDK 217

  Fly   196 VIFV-DFGHSSLQASACAFTKGKLKMLASTWDQ-IGGRDIDLALGDYFAKEFQERYKINAKTNAR 258
            :|.| |.|..:...|.....||..::.::..|. :||.|.|.||..:...||::...::...:.:
 Worm   218 IIAVYDLGGGTFDVSILEIQKGVFEVKSTNGDTFLGGEDFDHALVHHLVGEFKKEQGVDLTKDPQ 282

  Fly   259 ANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDID----VSSSMQRSQMEELCAPVLQRVEQTFK 319
            |..||....||.|.::| ::|:..:|:.....|..    ::..:.|::.|::...:::|..:..:
 Worm   283 AMQRLREAAEKAKCELS-STTQTDINLPYITMDQSGPKHLNLKLTRAKFEQIVGDLIKRTIEPCR 346

  Fly   320 RLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPAV 384
            :.|.:::::...|..|.:|||.||:|.|:..::::|.|..|..:|.||||:.|||:|.|:::.
 Worm   347 KALHDAEVKSSQIADVLLVGGMSRMPKVQATVQEIFGKVPSKAVNPDEAVAMGAAIQGAVLAG-- 409

  Fly   385 RVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVY-----G 444
                 .|||:....|..|  |.|....|.|          .::|:|.|...|...|.|:     |
 Worm   410 -----DVTDVLLLDVTPL--SLGIETLGGI----------MTKLITRNTTIPTKKSQVFSTAADG 457

  Fly   445 Q------------QVPYPDQTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKE 497
            |            ::...::.:|.:.:..:.|..||..| |::...|:.||||.:|
 Worm   458 QTQVQIKVFQGEREMATSNKLLGQFSLVGIPPAPRGVPQ-VEVTFDIDANGIVNVS--------- 512

  Fly   498 AEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGS 562
            |.:.....||....:..|
 Worm   513 ARDRGTGKEQQIVIQSSG----------------------------------------------- 530

  Fly   563 GADKKKKASKATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNK 627
                                 |.|...:.|..::..|....|.|..|.::..|..|..::|...|
 Worm   531 ---------------------GLSKDQIENMIKEAEKNAAEDAKRKELVEVINQAEGIIHDTEAK 574

  Fly   628 LQ--GGPFERYVVEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYE 690
            :.  .....:...||.|.||......|:|...|..|..:....|.:.|:|       ||..:.|:
 Worm   575 MTEFADQLPKDECEALRTKIADTKKILDNKDNETPEAIKEACNTLQQQSL-------KLFEAAYK 632

  Fly   691 QGPAAFDELKNS 702
            ...|     |||
 Worm   633 NMAA-----KNS 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	127/385 (33%)
		HSP70	3..682	CDD:278441	183/705 (26%)
hsp-6	NP_001370558.1	dnaK	30..646	CDD:234715	190/727 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900