Protein Alignment Hsp110 and hsp-110

DIOPT Version :10

• Sequence 1: NP_001189103.1
• Gene: Hsp110 / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_498868.1
• Gene: hsp-110 / 176195
• WormBaseID: WBGene00016250
• Length: 776
• Species: Caenorhabditis elegans
• Alignment Length: 831
• Identity: 337/831 - (40%)
• Similarity: 478/831 - (57%)
• Gaps: 66/831 - (7%)

  Fly     1 MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVG 65
            |||:|.|.||.:||:..||.||||.:.|||||.|||:.|:|..|.|.:||||:....||:||||.
 Worm     1 MSVLGFDIGNLNCYIGVARQGGIEVITNDYSLHATPACVSFGPKDRSMGVAARQAVTTNIKNTVI 65

  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130
            .||.|:||||:||..|..:..||.:|....:..||::|:||||...|.|||:.|.|.|||:....
 Worm    66 NFKHLIGRKFSDPVAQRFIPFIPCKVVKLPNDDIGVQVSYLGEPHTFTPEQVLAALLTKLRTIVE 130

  Fly   131 AAMQ--TQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFED-- 191
            :.:.  .:|:|||:|.|.:||:.:|:|:|.|.|.||||.||::|||||.|||||.||.||.|:
 Worm   131 SQLSDVKKVSDCVLAVPSYFTDVQRRAVLSAIQYAGLNSLRIVNETTAIALAYGIYKQDLPEEDA 195

  Fly   192 KPRNVIFVDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKT 255
            |.|||:|:|.||||.|||..||.:|||:|:.:::| :.||...|..:.::|.|||:.:|.|:|.|
 Worm   196 KSRNVVFLDIGHSSTQASLVAFNRGKLQMVNTSYDLESGGIWFDALIREHFRKEFKTKYGIDAAT 260

  Fly   256 NARANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKR 320
            :.|..||||.|.|::|||||||.|.:|||||||::|.||:..|||.:.|:|.||:..|::|....
 Worm   261 SPRPWLRLLDECERVKKQMSANQTPIPLNIECFMEDKDVTGKMQRQEFEDLAAPIFNRIKQVLIN 325

  Fly   321 LLAES-KLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPAV 384
            |.|:. .::.::|..:||||||||||.::::::.:|.|...||:||||||:||||:||||:||..
 Worm   326 LFADGVSIKPEEIDEIEIVGGSSRIPMIREIVKDLFGKEPKTTMNQDEAVARGAAMQCAILSPTF 390

  Fly   385 RVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVYGQQ--V 447
            |||||.:.|.|.|.:::.|:|.|... ||.::|......|||:|:::.|.|||||...|.|.  |
 Worm   391 RVREFAIKDTQPYRIRLSWNSTGENG-GENDVFSPRDEVPFSKLVSLLRSGPFNVEAHYAQPNVV 454

  Fly   448 PYPDQTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEE 512
            |:....||.|||...:|...|..|.||:|||:|.:||..|:|||:.|.:..||..|.|.:...:.
 Worm   455 PHNQVHIGSWKVNGARPGADGGNQKVKVKVRVNPDGIFTIASATMYEPRIVEEVPAEAMEVDGDA 519

  Fly   513 KPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELP 577
            |       |..||:..:..                                  ||.|.     :|
 Worm   520 K-------TEAPAEPLEPV----------------------------------KKTKL-----VP 538

  Fly   578 LECTTHGFSPV--DLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEA 640
            ::.......||  |:..:...|.:|..:|.:|..:.||||:|||:||:||:|: ...:..::..|
 Worm   539 VDLEVIESIPVSYDVQKFHNLELQMQESDAREKAKADAKNSLEEYVYEMRDKV-SDQYAEFITPA 602

  Fly   641 EREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAAFDELKNSIAI 705
            ..::..|.|...|:|||::|||.|||:|..||..|.....|:..|..:.|....|||....||..
 Worm   603 AADEFRSVLTSTEDWLYDEGEDAERDVYEKRLSELKAVGTPVVERYRESETRKPAFDSFDQSIMR 667

  Fly   706 ARLAVAEFRKGVPKYDHLTETEFINISETADKAQSWLDANLPKFTQSPRTADSPVQIS-AVRQEV 769
            .|.|..::..|.|.|.||...|...:....:..:.|||....|.....:| |:||..: .:.|..
 Worm   668 VRKAYEDYANGGPTYAHLDSKEMEKVINAIEDKKKWLDEARHKQETRSKT-DAPVVFTEEILQNK 731

  Fly   770 QTLNSCVSSVINRAKPKPTPAKTATPPKDEANAEQNGGEPAANSGDKMDVD 820
            ....:.|:.::|:.|| ..||    |||.|......|.:|.:..|: ||||
 Worm   732 NVFENVVNPILNKKKP-AAPA----PPKKEEPQPAAGDQPQSQPGE-MDVD 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp110	NP_001189103.1	ASKHA_NBD_HSP70_HSPA4_like	4..378	CDD:466826	190/379 (50%)
hsp-110	NP_498868.1	HSP70	3..650	CDD:394970	295/694 (43%)