Protein Alignment Hsc70Cb and F44E5.5

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_496510.1
• Gene: F44E5.5 / 174806
• WormBaseID: WBGene00009692
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 189/657 - (28%)
• Similarity: 318/657 - (48%)
• Gaps: 91/657 - (13%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            ||||.|.....|...::|.:|.|||....:.|||:|||...:|::|.|||:|...|.:|||...|
 Worm     7 IGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDAK 71

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:||:|::..||.:....|..|:.: .|...|:|...||.:.|.||:::||:..|:|||:...:
 Worm    72 RLIGRRFDESTVQSDCKHWPFGVKGK-QGKPVIEVEVKGEKRQFNPEEISAMVLQKMKETAETYL 135

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            ...|.|.||..|.:|.:::|:|..|||.|||||.:|::||.||.|||||..|.  .:|: :||:.
 Worm   136 GHTVKDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKG--IQDE-KNVLI 197

  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTW--DQIGGRDIDLALGDYFAKEFQERYKINAKTNARANL 261
            .|.|..:...|..:..:|.:..:.||.  ..:||.|.|..:..:|..||:.:...:...|.||..
 Worm   198 FDLGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDQRMLQHFMNEFKRKTGKDISPNPRAIR 262

  Fly   262 RLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESK 326
            ||.|..|:.|:.:| :|::..:.::...:.||:.:.:.|::.|||||.:.::..:..::.|.::|
 Worm   263 RLRTACERAKRTLS-SSSEACVEVDSLFEGIDLCTKITRARFEELCADLFRKTLEPVEKALRDAK 326

  Fly   327 LQLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIMSPAVRVREFG 390
            |....|..|.:||||:|:|.:::|::..|| |..:.::|.||||:.|||:|.|::|   .|::..
 Worm   327 LDKSKIDEVVLVGGSTRVPKIQKLLKDFFNGKELNCSINPDEAVAFGAAVQAAVLS---GVKDET 388

  Fly   391 VTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGP----------------FNV 439
            :.|:....|..|  |.|....|.:          .:.|:..|.:.|                .::
 Worm   389 IKDVLLVDVAPL--SLGIETAGGV----------MTNLIDRNTRIPTKACKTFTTYADNQPGVSI 441

  Fly   440 SIVYGQQVPYPD-QTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISS----------ATLV 493
            .:..|::....| ..:|.:::..:.|..||..| :::...|:.|||:.:|:          .|:.
 Worm   442 QVYEGERAMTRDNHRLGTFELSGIPPAPRGVPQ-IEVTFDIDANGILNVSAEDKSTGKSNRITIQ 505

  Fly   494 EKK----EAEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAY------CENEDDNNTSTASSPG 548
            .:|    :::......|....|::.|:|....  .|..|.|||      ..:|..:..||..:..
 Worm   506 NEKGRLTQSDIDRMVHEAKQFEKEDGEQRERV--QARNQLEAYAFQIKQALDEYSSKLSTEDASR 568

  Fly   549 GQGWAQRVKGWFGSG--ADKKKKASKATELPLECT-----------------------THGFSPV 588
            .:........|..|.  |:|.:..:|..||...|.                       |.||:|
 Worm   569 AKEAVDETLRWLDSNSLAEKDEIEAKDKELKSVCQSILTKMHQSGQSSASAGCAGNPGTAGFNP- 632

  Fly   589 DLSNYTQ 595
              :||.|
 Worm   633 --NNYPQ 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	137/379 (36%)
		HSP70	3..682	CDD:278441	189/657 (29%)
F44E5.5	NP_496510.1	PTZ00009	1..645	CDD:240227	189/657 (29%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	137/379 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810