Protein Alignment Hsp110 and T24H7.2

DIOPT Version :10

• Sequence 1: NP_001189103.1
• Gene: Hsp110 / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_495249.1
• Gene: T24H7.2 / 174033
• WormBaseID: WBGene00020781
• Length: 925
• Species: Caenorhabditis elegans
• Alignment Length: 943
• Identity: 224/943 - (23%)
• Similarity: 381/943 - (40%)
• Gaps: 190/943 - (20%)

  Fly     1 MSVIGIDFGNESCYVAAARSG-GIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTV 64
            ::.:.||.|.:...:...:.| .::...|..|.|.||:.|......|....||...||.......
 Worm    24 LAAMTIDLGTQFLKIGIVKPGIPMDIALNTESRRKTPNVVMIQDGHRTFADAAIGMQVRYPHLVH 88

  Fly    65 GGFKRLLGRKFNDPHVQ--------HELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAML 121
            |....|:|:....|..:        .|:...|     :...||..|:.  ||.  :..|.||||:
 Worm    89 GQLNDLVGKSTQHPSFELFKRRNTFFEVDDAP-----KNASSINFKLG--GES--YTVEALTAMI 144

  Fly   122 FTKLKE-TSAAAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYK 185
            ....|: |...|...::.|.||..||:||.|||.|:..|||:|||.||:|:|:.||.||::|.::
 Worm   145 LANAKKFTEEYAQAAEIKDVVITVPVYFTPAERLAVERAAQMAGLTVLQLINDGTAAALSHGIFR 209

  Fly   186 NDLFEDKPRNVIFVDFGHSSLQASACAF--------TKGKLKMLASTWDQ-IGGRDIDLALGDYF 241
            .....:||:.::..|.|.:...|:...|        .:.|:.:|...:|: :||.::...|.|:.
 Worm   210 RKEIGEKPQRLMVYDMGAAKTTATIVEFKLVKEKYEKQPKMTVLGVGFDRTLGGIEMTNRLRDHL 274

  Fly   242 AKEFQERYKINAK--TNARANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQME 304
            .:.|::.||...|  ||.||..:...|.|:||:.:|||:... ..||...:|||....:.|....
 Worm   275 IEMFEKNYKPKTKVNTNRRAMTKFSKEAERLKQVLSANAEHF-AQIESAHEDIDAKLKVTREDFN 338

  Fly   305 ELCAPVLQRVEQTFKRLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQ-VFNKPASTTLNQDEA 368
            .|.:.:..|..:..::.|..:::.:|||....::|..:|:|.|:::::: :..|.....||.|||
 Worm   339 HLISDMESRFGEPIEQALRMAQIPIDDIDQFVLMGAGTRVPKVQEIVQKTIGTKEIGKFLNTDEA 403

  Fly   369 VSRGAALQCAIMSPAVRVREFGVTD-----IQNYAVKVLWDSEGSAAPGEIEIFPQ-------YH 421
            |:.||..|.|.:|...:|:.|.:.:     ::.:.|..:.|.:.....||..:...       |.
 Worm   404 VAMGALFQAAHLSKGFKVKPFNIEEKVIFPVEVHFVSKIRDEKTEEITGEKNVVKTLFAANSVYP 468

  Fly   422 ASPFSRLLTINRKGPFNVSIVYGQQVPYPDQTI----------------GVWKVKDVKPTERGEG 470
            ..|.:..|| :....|:|::.||:...:..|.:                |:.:....:.:|..|.
 Worm   469 THPKTISLT-SYSDDFSVALKYGKIESFTKQQVQEIGSLLDNLVDVEISGLSEALKNRSSEESEF 532

  Fly   471 QDVKLKVRINNNGIV-------------------------LISSAT-------------LVEKKE 497
            :.||:...::.:|||                         |.||.|             ..|:|.
 Worm   533 KGVKVSFIVDASGIVRVRRAEALFEPKSGLVGSIASTISGLFSSKTEEGEPTTDDSTPQSTEEKT 597

  Fly   498 AEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGS 562
            .|:.:...|.:..|.:|....|:|.|      |:...||.:.|.|:       |.|..||
 Worm   598 EEKESVKVEDSTPEPEPETPVNSTSE------ESPKTNETEKNASS-------GNATEVK----- 644

  Fly   563 GADKKKKASKATELP----LECTTHGFSPVDLSNYTQQESK--MIGNDQKE---TERIDAKNALE 618
              :|||      |||    |..|....|....:.|..||.|  |....:||   :||...:|.||
 Worm   645 --EKKK------ELPSIVRLRITNKYPSAFVPNKYDVQEEKRRMEAFAEKERLASERAAVENELE 701

  Fly   619 EFVYDMRNKLQGGPFERYVVEAEREKIVSQLNDLENWLYED-GEDCERDIYTSRLQAL------- 675
            .|.::....|:...|..|:.:.|:.|:...:..:..||.:| .:|.....:|..|..|
 Worm   702 SFNFECSQYLEETEFTDYMADEEKTKLEDSVKRIRAWLEDDVTKDTPTKDFTDNLLELKNVVRSV 766

  Fly   676 -----HQKTDPIKLRA---------------SDYEQGPAAF-----DELKNSIAIARLAVAEFRK 715
                 |.|..|.||::               ::.::..|.|     |.||:.:...::.|.:.||
 Worm   767 KKRQEHDKAVPEKLKSLETLLETTFSLTTLGNNVDEEKALFKKEDRDGLKSKLDKLKIWVTDVRK 831

  Fly   716 GV---PKYDHLT------ETEFINISETADKAQSWLDANLPKFTQSPRTA-DSPVQISAVRQEVQ 770
            .:   .|.|...      :|:..|::...|:...    .:.|.|.....| |..:.|..:.:|.:
 Worm   832 HLDLKKKTDDFNFTGKDIDTKTKNLNREVDRFMK----KMKKITTLDDLAKDGKIDIDTIVEEAE 892

  Fly   771 TLNSCVSSVINRAKPKPTPAKTATPPKDEANAE 803
            .         .:|:......|.:|...:|:..|
 Worm   893 K---------KKAEQDKKKEKKSTKKANESKVE 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp110	NP_001189103.1	ASKHA_NBD_HSP70_HSPA4_like	4..378	CDD:466826	114/395 (29%)
T24H7.2	NP_495249.1	ASKHA_NBD_HSP70_HYOU1	25..413	CDD:466828	114/397 (29%)