Protein Alignment Hsc70Cb and hsp-70

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 730
• Identity: 193/730 - (26%)
• Similarity: 330/730 - (45%)
• Gaps: 139/730 - (19%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            ||||.|.....|...::|.:|.|||....:.|||:|||...:|::|.|||:|...|.:|||...|
 Worm     7 IGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDAK 71

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:||:|::..||.::...|..|:.: .|...::|...||.:.|..|:::||:..|:|||:.|.:
 Worm    72 RLIGRRFDEETVQSDIKHWPFTVKGK-QGKPVVEVEVKGEKREFNAEEISAMVLQKMKETAEAVL 135

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            ...|.|.||..|.:|.:::|:|..|||.|||||.:|::||.||.|||||..|....|   :|::.
 Worm   136 GHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGITDE---KNILI 197

  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTW--DQIGGRDIDLALGDYFAKEFQERYKINAKTNARANL 261
            .|.|..:...|..:..:|.:..:.||.  ..:||.|.|..:..:|..||:.:...:..:|.||..
 Worm   198 FDLGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFKRKTGKDISSNPRAIR 262

  Fly   262 RLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESK 326
            ||.|..|:.|:.:| :||:..:.::...|..|..|.:.|::.|||||.:.::..:..::.|.::|
 Worm   263 RLRTACERAKRTLS-SSTEATVEVDSLFDGTDFYSKITRARFEELCADLFRKTLEPVEKALRDAK 326

  Fly   327 LQLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIMSPAVRVREFG 390
            .....|..|.:||||:|||.:::|:::.|| |..:.::|.||||:.|||:|.|::|   .|::..
 Worm   327 TDKGRIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAVLS---GVKDDT 388

  Fly   391 VTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGP----------------FNV 439
            :.|:  ..|.|:..|.|....|.:          .:.|:..|.:.|                .::
 Worm   389 IKDV--LLVDVVPLSHGIETAGGV----------MTNLIDRNTRIPAKASKTFTTYADNQPGVSI 441

  Fly   440 SIVYGQQVPYPD-QTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAA 503
            .:..|::....| ..:|.:::..:.|..||..| |.:...|:.|||:.:|:|
 Worm   442 QVYEGERAMTRDNHRLGTFELTGIPPAPRGVPQ-VDVTFDIDANGILNVSAA------------- 492

  Fly   504 AAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKK 568
                          ..:||.               :|..|..:..|:
 Worm   493 --------------DKSTGR---------------SNRITIRNEKGR------------------ 510

  Fly   569 KASKATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPF 633
                            .|..|:.....:..:....|..:.:||.::|.||.:.:.::..|:....
 Worm   511 ----------------LSQADIDRMVNEAKQFEREDAAQRDRISSRNQLEAYAFQVKQALEEHGS 559

  Fly   634 ERYVVEAEREKIVSQLNDLENWL----YEDGEDCE------RDIYTSRLQALHQKT--------D 680
            .....:|:|.|  ..:.|...|:    ..|.::.|      :.|....|..:||:.        :
 Worm   560 LLSAEDAKRAK--DAVEDTLRWMERNTLADKDEIEAKDKELKSICQDILTKMHQQEAQSGSGCGN 622

  Fly   681 PIK--LRASDYEQGP 693
            |..  ..:|:|.|||
 Worm   623 PGSGGFHSSNYPQGP 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	137/379 (36%)
		HSP70	3..682	CDD:278441	187/715 (26%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	193/730 (26%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	137/379 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810