Protein Alignment Hsp110 and hspa1b

DIOPT Version :10

• Sequence 1: NP_001189103.1
• Gene: Hsp110 / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: XP_002937685.2
• Gene: hspa1b / 100485441
• XenbaseID: XB-GENE-5915622
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 690
• Identity: 194/690 - (28%)
• Similarity: 346/690 - (50%)
• Gaps: 101/690 - (14%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            ||||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|..|||...|
 Frog     8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPHNTVFDAK 72

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:|||:::|.||.::...|.:|.:.| |...:.|.|.||.:.|.||::::|:.||:|||:.|.:
 Frog    73 RLIGRKYDEPVVQSDMKHWPFKVISDG-GKPKVTVEYKGEGKSFSPEEISSMVLTKMKETAEAYL 136

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            ..:|.:.||..|. |.:::|:|..||..||||||||::||.||.|:|||..|:...|   ||::.
 Frog   137 GYKVTNAVITVPAXFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKSGRGE---RNILI 198

  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANLR 262
            .|.|..:...|......|..::.|:..| .:||.|.|..:.::|.:||:.::|.:...|.||..|
 Frog   199 FDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISPNKRALRR 263

  Fly   263 LLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKL 327
            |.|..|:.|:.:| :||:..:.|:...:.||..:|:.|::.|||||.:.:...:..::.:.::||
 Frog   264 LRTACERAKRTLS-SSTQASIEIDSLFEGIDFYTSITRARFEELCADLFRGTLEPVEKAMRDAKL 327

  Fly   328 QLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIM--SPAVRVREF 389
            ....||.:.:||||:|||.|::|::..|| |..:.::|.||||:.|||:|.||:  ..:..|::.
 Frog   328 DKSQIHEIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILMGDKSENVQDL 392

  Fly   390 GVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHAS-PFSRLLTI-----NRKGPFNVSIVYGQQVP 448
            .:.|:...::.:      ..|.|.:.:..:.:.: |..:..|.     |:.|.. :.:..|::..
 Frog   393 LLLDVAPLSLGL------ETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVL-IQVYEGERAM 450

  Fly   449 YPDQT-IGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEE 512
            ..|.. :|.:.:..:.|..||..| :::...|:.|||:.:|               |.::::.::
 Frog   451 TKDNNLLGKFDLTGIPPAPRGVPQ-IEVTFDIDANGILNVS---------------AVDKSSGKQ 499

  Fly   513 KPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELP 577
            .....||:.|.
 Frog   500 NKITITNDKGR------------------------------------------------------ 510

  Fly   578 LECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAER 642
                   .|..::....|:..|...:|:::.|:|.|||:||.:.::|::.::....:..:.:.::
 Frog   511 -------LSKEEIERMLQEADKYKADDEQQREKIAAKNSLESYAFNMKSTVEDNNIKDKISDNDK 568

  Fly   643 EKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPI 682
            :.|:.:..::.:|| |..:..|::.||.:.:.|.:..:||
 Frog   569 KSILDKCQEVISWL-EQNQLAEKEEYTHKQKELEKLCNPI 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp110	NP_001189103.1	ASKHA_NBD_HSP70_HSPA4_like	4..378	CDD:466826	146/375 (39%)
hspa1b	XP_002937685.2	PTZ00009	2..643	CDD:240227	194/690 (28%)