Protein Alignment Hsc70Cb and hsp70.1

DIOPT Version :9

• Sequence 1: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_001349288.1
• Gene: hsp70.1 / 100126123
• ZFINID: ZDB-GENE-990415-91
• Length: 643
• Species: Danio rerio
• Alignment Length: 702
• Identity: 194/702 - (27%)
• Similarity: 349/702 - (49%)
• Gaps: 102/702 - (14%)

  Fly     4 IGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFK 68
            ||||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||.|||||...|..|||...|
Zfish     9 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAK 73

  Fly    69 RLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAM 133
            ||:||:|:||.||.::.....:|.:.| |...:.|.:.||::.|.||::::|:..|:||.:.|.:
Zfish    74 RLIGRRFDDPVVQSDMKHWSFKVVSDG-GKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAEAYL 137

  Fly   134 QTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIF 198
            ..:|.:.||..|.:|.:::|:|..||..||||||||::||.||.|:|||..|.   :...|||:.
Zfish   138 GQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKG---KSSERNVLI 199

  Fly   199 VDFGHSSLQASACAFTKGKLKMLASTWD-QIGGRDIDLALGDYFAKEFQERYKINAKTNARANLR 262
            .|.|..:...|......|..::.|:..| .:||.|.|..:.::|.:||:.::|.:...|.||..|
Zfish   200 FDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRR 264

  Fly   263 LLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKL 327
            |.|..|:.|:.:| :|::..:.|:...:.||..:|:.|::.||||:.:.:......::.|.::|:
Zfish   265 LRTACERAKRTLS-SSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALKDAKM 328

  Fly   328 QLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIM--SPAVRVREF 389
            ....||.:.:||||:|||.:::|::..|| :..:.::|.||||:.|||:|.||:  ..:..|::.
Zfish   329 DKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDL 393

  Fly   390 GVTDIQNYAVKVLWDSEGSAAPGEIE---IFPQYHASPFSRLLTINRKGPFNVSIVYGQQVPYPD 451
            .:.|:...::.:  ::.|......|:   ..|......|: ..:.|:.|.. :.:..|::....|
Zfish   394 LLLDVAPLSLGI--ETAGGVMTALIKRNTTIPTKQTQTFT-TYSDNQPGVL-IQVFEGERAMTKD 454

  Fly   452 QT-IGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEEKPG 515
            .. :|.:::..:.|..||..| :::...|:.|||:.:|               ||:::..::...
Zfish   455 NNLLGKFELTGIPPAPRGVPQ-IEVTFDIDANGILNVS---------------AADKSTGKQNKI 503

  Fly   516 DQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELPLEC 580
            ..||:.|.
Zfish   504 TITNDKGR--------------------------------------------------------- 511

  Fly   581 TTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAEREKI 645
                .|..::....|:..|....|..:.|:|.|||:||.:.::|:|.::....:..:.|.:::::
Zfish   512 ----LSKEEIERMVQEADKYKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRV 572

  Fly   646 VSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPI--KLRASDYEQG-PA 694
            :.:.|:..:|| |:.:..:::.|..:|:.|.:..:|:  ||    |:.| ||
Zfish   573 IEKCNEAVSWL-ENNQLADKEEYEHQLKELEKVCNPVISKL----YQGGMPA 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	141/380 (37%)
		HSP70	3..682	CDD:278441	187/685 (27%)
hsp70.1	NP_001349288.1	HSP70	5..643	CDD:331774	194/702 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810