Protein Alignment CG6661 and aldh1a3

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001038210.1
• Gene: aldh1a3 / 751785
• ZFINID: ZDB-GENE-061128-2
• Length: 513
• Species: Danio rerio
• Alignment Length: 561
• Identity: 132/561 - (23%)
• Similarity: 219/561 - (39%)
• Gaps: 114/561 - (20%)

  Fly    43 QDEDQQEVEPDSQPAEENPSIHRNQRVLVNHAIQEIQHRPLEVPTIIGDDTVYTMDTQRVCCPHH 107
            ::.|.:...|...|.....:..::.::.:|:. .....:..:.|||.....|...|.:.
Zfish     8 ENGDSRNTSPPPLPQPVKITEIKHTKIFINNE-WHTSSKGKQFPTINPATGVKICDIEE------ 65

  Fly   108 LQTNLAHVYYANRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLMMTLS 172
                      |::..::.|:|:|.:|         .||.::|||.     :...|.|:     |:
Zfish    66 ----------ADKADVDEAVKAAKAA---------GQRGSVWRRM-----DASSRGRL-----LN 101

  Fly   173 KTADDATRDIRRLLTSLRAN-----------ADYLEHLSELRF------EIQG-----DMNVFPS 215
            :.||...|: |.:|.:|.:.           .|....:..||:      :|.|     |.| |..
Zfish   102 RLADLLERE-RAVLATLESKDTGKPFLHAFFVDLDGSIKTLRYYAGWTDKIHGKTMPVDEN-FVC 164

  Fly   216 FHLRPMDGFVAALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYL-IFRAFQEAGLPSG 278
            |......|...|:.|:....|.....:.||| .||||:..|: |..|::.| :....:|||.|.|
Zfish   165 FTKHEPIGVCGAIIPWNFPLLMLMWKIAPALACGNTVVLKPA-EQTPLTALHVAALIKEAGFPPG 228

  Fly   279 VINFVPANERLFLDTITDAVHFAGLNTQASAAFYRH--VHKLV---SDRMERYI-------CFPR 331
            |:|.||                 |....|.||...|  :.||.   |..:.:.:       ...|
Zfish   229 VVNVVP-----------------GFGPTAGAAIAGHMNIDKLAFTGSTEVGQLVKAAAASSNLKR 276

  Fly   332 LVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQL 396
            :..|..|:|...|.|.:.::..|..|.:.||...||...:.||:||...::.......||..:.:
Zfish   277 VTLELGGKNPCIVFADSDLQLAVEETQKGAFFNQGQACTAASRVYVQEPVYEEFVRLSVERAKNI 341

  Fly   397 TIGDPIESETDIGAMVHINDFRRMQKLLQRTK----NMEQLCGGSCDDSTGRFVDPTIVRVSDPL 457
            .||||:|..|..|..:..:.|.::..|:...|    .:|  .||...:..|.|:.|||  .||..
Zfish   342 VIGDPMEPRTSHGPQIDQHQFEKILALVDSGKKEGAKLE--FGGCAVEDRGLFIHPTI--FSDVK 402

  Fly   458 DPLLC--EPCCGPF--LPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSA 518
            |.:..  |...||.  :..|....|....     ||.|::.|:.::|....:..:..  ...:.|
Zfish   403 DHMRIAKEEIFGPVQCIMKFECQQDVIDR-----ANSSQFGLTAAVFTRDVQRAMSV--SAALEA 460

  Fly   519 SNLYVNERCTGSTYGLTPFGGNRLSGTNDKSGSAYFLMRWS 559
            ..::||  |..:.:..|||||.::||...:.|. |.|..::
Zfish   461 GTVWVN--CYNALHAQTPFGGYKMSGNGRELGE-YALAEYT 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	129/536 (24%)
aldh1a3	NP_001038210.1	ALDH_F1AB_F2_RALDH1	28..506	CDD:143459	129/541 (24%)