Protein Alignment CG6661 and ALDH8A1

DIOPT Version :9

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_072090.1
• Gene: ALDH8A1 / 64577
• HGNCID: 15471
• Length: 487
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 115/488 - (23%)
• Similarity: 201/488 - (41%)
• Gaps: 89/488 - (18%)

  Fly    95 YTMDTQRVCCPHHLQTNLAHVYYANRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEED 159
            |...|..|.|         .|..:.:.:||||:|:|..|..:||.....:|..:..:.|.::|:.
Human    28 YDPSTGEVYC---------RVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQS 83

  Fly   160 ELRLRVFLMMTLSKTADDA-------TRDIRRLLTSLRANA-DYLEHLSE-LRFEIQGDMNVFPS 215
               |..|..   :::.|..       |.||.|.:.:.|..| ..|.|.|| .:.:..|.|:
Human    84 ---LEEFAQ---AESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMH---- 138

  Fly   216 FHLRPMDGFVAALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSGV 279
            :.:|...|....::|:.......:..:.||: .||||:..||...:..::::.:...:||:|.||
Human   139 YTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGV 203

  Fly   280 INFV-----PANERLFLDTITDAVHFAGLN------TQASAAFYRHVHKLVSDRMERYICFPRLV 333
            :|.|     ...|.|........:.|.|..      ||.||.   |..|              |.
Human   204 VNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP---HCKK--------------LS 251

  Fly   334 AECPGQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTI 398
            .|..|:|...:...|.::..:.|||:::|...|:.....||::|..|::....:..||||.:..:
Human   252 LELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKV 316

  Fly   399 GDPIESETDIGAMVHINDFRRMQKLLQR--TKNMEQLCGGSCD-------DSTGRFVDPTIVRVS 454
            |.|.:....|||::......:::..::|  .:..:..||...|       :..|.|:.||:  ::
Human   317 GIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTV--IT 379

  Fly   455 DPLDPLLCEPCC------GPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQ 513
            |..|    |.||      ||...|..:  ||..|.:: .||..:|.|:.::::|....:.....:
Human   380 DIKD----ESCCMTEEIFGPVTCVVPF--DSEEEVIE-RANNVKYGLAATVWSSNVGRVHRVAKK 437

  Fly   514 LRMSA--SNLYVNERCTGSTYGLTPFGGNRLSG 544
            |:...  :|.::.....      .||||.:.||
Human   438 LQSGLVWTNCWLIRELN------LPFGGMKSSG 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	115/488 (24%)
ALDH8A1	NP_072090.1	ALDH_F8_HMSADH	27..485	CDD:143412	115/488 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810