DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6661 and Aldh9a1

DIOPT Version :9

Sequence 1:	NP_648686.3	Gene:	CG6661 / 39556	FlyBaseID:	FBgn0036403	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_071609.2	Gene:	Aldh9a1 / 64040	RGDID:	68409	Length:	497	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	112/466 - (24%)
Similarity:	207/466 - (44%)	Gaps:	74/466 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 ANRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEE--DELRLRVFLMMTLS--KTADDA 178
            :..|::..|:::|.:|...||.....:|..:...||.||:|  ||    :.:|.|::  |:..:|
  Rat    46 SGEKEVNLAVENAKAAFKIWSKKSGLERCQVLLEAARIIKERRDE----IAIMETINNGKSIFEA 106

  Fly   179 TRDIRRLLTSLRANADYLEHLSELRFEIQGDMNVFP--SF---HLRPMD---GFVAALAPFESVA 235
            ..|:.   ||.:.    ||:.:.|...:.|:....|  ||   ...|:.   |..|...||:...
  Rat   107 RLDVD---TSWQC----LEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCLGIGAWNYPFQIAC 164

  Fly   236 LSSSLALCPALMGNTVLWNPSLEVAPVSYLIF-RAFQEAGLPSGVINFVP--ANERLFLDTITDA 297
            ..|:.||.   .||.:::.|| ...|||.|:. ..:.:||.|:|:.|.|.  |....||....|.
  Rat   165 WKSAPALA---CGNAMIFKPS-PFTPVSALLLAEIYTKAGAPNGLFNVVQGGAATGQFLCQHRDV 225

  Fly   298 --VHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQA 360
              |.|.|     |......:.::.:..::      .:..|..|::...:.:...:::.|...:.|
  Rat   226 AKVSFTG-----SVPTGMKIMEMAAKGIK------PITLELGGKSPLIIFSDCNMKNAVKGALLA 279

  Fly   361 AFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETDIGAMVHINDFRRMQKLLQ 425
            .|...||...:.:|::|...:.....:|:|..|:::.||||:..:|.:|.:::.....|:...::
  Rat   280 NFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPLLEDTRMGPLINAPHLERVLGFVR 344

  Fly   426 RTKNMEQ----LCGG---SCDD---STGRFVDPTIVRVSDPLDPLLC--EPCCGPFLPVFVYSDD 478
            ..|  ||    ||||   :.:|   ..|.::.|.|  :::..|.:.|  |...||.:.:..:..:
  Rat   345 SAK--EQGATVLCGGEPYAPEDPKLKHGYYMTPCI--LTNCTDDMTCVKEEIFGPVMSILTFETE 405

  Fly   479 SFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGLT----PFGG 539
              :|.|: .||.:.:.|:..:| ::|....|.: ...:.|...|:|      .|.::    ||||
  Rat   406 --AEVLE-RANDTTFGLAAGVF-TRDIQRAHRV-AAELQAGTCYIN------NYNVSPVELPFGG 459

  Fly   540 NRLSGTNDKSG 550
            .:.||...::|
  Rat   460 YKKSGFGRENG 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	112/466 (24%)
Aldh9a1	NP_071609.2	ALDH_F9_TMBADH	31..488	CDD:143409	112/466 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810