Protein Alignment CG6661 and Aldh1a3

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_444310.3
• Gene: Aldh1a3 / 56847
• MGIID: 1861722
• Length: 512
• Species: Mus musculus
• Alignment Length: 549
• Identity: 130/549 - (23%)
• Similarity: 221/549 - (40%)
• Gaps: 102/549 - (18%)

  Fly    51 EPDSQPAEENPSIHRNQRVLVNHAIQEIQHRPLEVPTIIGDD----------TVYTMDT-QRVCC 104
            :||.:|    |::.|..|.|      |::...:    .|.:|          ..|...| :::|
Mouse    12 QPDGKP----PALPRPIRNL------EVKFTKI----FINNDWHESKSGRKFATYNPSTLEKIC- 61

  Fly   105 PHHLQTNLAHVYYANRKQIEAAIKSALSA--QGT-WSLVPIAQRLAIWRRAATIIEEDELRLRVF 166
                     .|...::..::.|:::|.:|  :|: |..:....|..:..:.|.::|.|..
Mouse    62 ---------EVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLVERDRA----- 112

  Fly   167 LMMTLSKTADDATRDIRRLLTSLRANADYLEHLSELRFEIQG-----DMNVFPSFHLRPMDGFVA 226
            ::.|| :|.|.....:......|........:.:....:|||     |.||.......|: |...
Mouse   113 ILATL-ETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVVCFTRHEPI-GVCG 175

  Fly   227 ALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYLIFRA-FQEAGLPSGVINFVPANERL 289
            |:.|:....|..:..|.||| .||||:..|: |..|::.|...: .:|.|.|.||:|.||
Mouse   176 AITPWNFPLLMLAWKLAPALCCGNTVVLKPA-EQTPLTALYLASLIKEVGFPPGVVNIVP----- 234

  Fly   290 FLDTITDAVHFAGLNTQASAAFYRH-------------VHKLVSDRMERYICFPRLVAECPGQNF 341
                        |......||...|             |.|||.:...| ....|:..|..|:|.
Mouse   235 ------------GFGPTVGAAISSHPQINKIAFTGSTEVGKLVREAASR-SNLKRVTLELGGKNP 286

  Fly   342 HFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESET 406
            ..|.|.|.::..|....|..|...||...:.||::|...::.......||..::..:|||.:::|
Mouse   287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKT 351

  Fly   407 DIGAMVHINDFRRMQKLLQRTK----NMEQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLC--EPC 465
            :.|..:....|.::.:|::..|    .:|  ||||..:..|.|:.||:  .||..|.:..  |..
Mouse   352 EQGPQIDQKQFDKILELIESGKKEGAKLE--CGGSAMEDRGLFIKPTV--FSDVTDNMRIAKEEI 412

  Fly   466 CGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGS 530
            .||..|:..:.  :..|.:| .||.:.|.|:.::|....:..|.....|  .:..:::|  |..:
Mouse   413 FGPVQPILKFK--NLEEVIK-RANSTDYGLTAAVFTKNLDKALKLAAAL--ESGTVWIN--CYNA 470

  Fly   531 TYGLTPFGGNRLSGTNDKSGSAYFLMRWS 559
            .|...||||.::||...:.|. |.|..::
Mouse   471 FYAQAPFGGFKMSGNGRELGE-YALAEYT 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	125/532 (23%)
Aldh1a3	NP_444310.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		4/13 (31%)
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	124/531 (23%)