Protein Alignment CG6661 and ALDH7A1

DIOPT Version :9

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001173.2
• Gene: ALDH7A1 / 501
• HGNCID: 877
• Length: 539
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 109/479 - (22%)
• Similarity: 190/479 - (39%)
• Gaps: 69/479 - (14%)

  Fly   104 CPHHLQTNLAHVYYANRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLM 168
            ||.:.:. :|.|..|:....|..:|.|..|...|:.:|..:|..|.|:....:.|....|...:.
Human    70 CPANNEP-IARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVS 133

  Fly   169 MTLSKTADDATRDIRRLLTSLRANADYLEHLSELRFEIQGDMNVFPS--------FHLRPMDGFV 225
            :.:.|...:...:::..:..    .||...||.:   |.|.  :.||        ....|: |.|
Human   134 LEMGKILVEGVGEVQEYVDI----CDYAVGLSRM---IGGP--ILPSERSGHALIEQWNPV-GLV 188

  Fly   226 AALAPFE-SVAL---SSSLALCPALMGNTVLW----NPSLEVAPVSYLIFRAFQEAGLPSGVINF 282
            ..:..|. .||:   ::::|:   :.||..||    ..||....|:.:|.:..::..||..:.:.
Human   189 GIITAFNFPVAVYGWNNAIAM---ICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSL 250

  Fly   283 ----------VPANERLFLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECP 337
                      :..:||:.|      :.|.| :||..    :.|..:|.:|      |.|.:.|..
Human   251 TCGGADIGTAMAKDERVNL------LSFTG-STQVG----KQVGLMVQER------FGRSLLELG 298

  Fly   338 GQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPI 402
            |.|.......|.:..||.:.:.||.|.|||...:..|:::..|:...:...|.:|..|:.:|:|.
Human   299 GNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPW 363

  Fly   403 ESETDIGAMVHINDFRRMQKLLQRTKNMEQ-----LCGGSCDDSTGRFVDPTIVRVSDPLDPLLC 462
            :.....|.: |..  :.:...|...:..::     :.||...|..|.:|:||||........:..
Human   364 DPNVLYGPL-HTK--QAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAH 425

  Fly   463 EPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERC 527
            .....|.|.||.:.::   |.:....|:.:..||.|||......|...|.........:.||...
Human   426 TETFAPILYVFKFKNE---EEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPT 487

  Fly   528 TGSTYGLTPFGGNRLSGTNDKSGS 551
            :|:..| ..|||.:.:|...:|||
Human   488 SGAEIG-GAFGGEKHTGGGRESGS 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	109/479 (23%)
ALDH7A1	NP_001173.2	ALDH_F7_AASADH	53..527	CDD:143448	109/479 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810