Protein Alignment CG6661 and aldh8a1

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001004540.1
• Gene: aldh8a1 / 447801
• ZFINID: ZDB-GENE-040912-3
• Length: 487
• Species: Danio rerio
• Alignment Length: 463
• Identity: 114/463 - (24%)
• Similarity: 198/463 - (42%)
• Gaps: 70/463 - (15%)

  Fly   121 KQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLM---------MTLSKTAD 176
            :::.||:::|..|...||....|.|..:..:.|.:|   |.||..|:.         :|.::..
Zfish    45 EEVNAAVRAAKEAFPDWSAKSPADRSKVLNKLADLI---EARLEEFVQAESKDQGKTITFARNV- 105

  Fly   177 DATRDIRRLLTSLRANA-DYLEHLSEL-RFEIQGDMNVFPSFHLRPMDGFVAALAPFESVALSSS 239
                ||.|...:.|..| ..|.|.::. :.:..|.:|    :.:|...|....::|:.......:
Zfish   106 ----DIPRSAYNFRFFASSVLHHTNDCSQMDHMGCLN----YTIRCPVGVAGLISPWNLPLYLLT 162

  Fly   240 LALCPAL-MGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSGVINFV-----PANERLFLDTITDAV 298
            ..:.||: .||||:..||...:..::::.:..:|||.|.||:|.|     .|.:.|........:
Zfish   163 WKIAPAVATGNTVVAKPSEMTSVTAWMMCQLLEEAGFPPGVVNIVFGTGPRAGDALVSHPDVPLI 227

  Fly   299 HFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFG 363
            .|.|....|         :|:::|...: | .:|..|..|:|...:.|.|.:|..:|.||:::|.
Zfish   228 SFTGSTATA---------RLITERSAPH-C-KKLSLELGGKNPAIIFADADMEQCISTTVRSSFS 281

  Fly   364 FAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETDIGAMVHINDFRRMQKLLQRTK 428
            ..|:.....||::|..|::|......||||.:...|.|.:...|.||::       .::.||:.|
Zfish   282 NQGEICLCTSRIFVERSVYPEFLTRFVEATRRWKTGVPSDPSNDNGALI-------SKEHLQKVK 339

  Fly   429 NMEQL---------CGGSCD-------DSTGRFVDPTIVRVSDPLDPLLCEPCCGPFLPVFVYSD 477
            ....|         ||...|       :..|.|:.|||:........|:.|...||...|..:.:
Zfish   340 GYITLALAEGAQVHCGEGVDKLALPQQNIGGYFMLPTIISGVKDSSALMQEEIFGPVTCVTPFDE 404

  Fly   478 DSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGLTPFGGNRL 542
            :   |.:...||..||.||.::: |:|...:|.:.: ::.|..::.|  |........||||.:.
Zfish   405 E---EEVISRANNVRYGLSATVW-SRDVGRVHRVAR-KLQAGLVWTN--CWLVRDLNLPFGGMKH 462

  Fly   543 SGTNDKSG 550
            ||...:.|
Zfish   463 SGIGREGG 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	114/463 (25%)
aldh8a1	NP_001004540.1	ALDH_F8_HMSADH	27..485	CDD:143412	114/463 (25%)