DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6661 and Ssadh

DIOPT Version :9

Sequence 1:	NP_648686.3	Gene:	CG6661 / 39556	FlyBaseID:	FBgn0036403	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001014665.1	Gene:	Ssadh / 43092	FlyBaseID:	FBgn0039349	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	451	Identity:	105/451 - (23%)
Similarity:	189/451 - (41%)	Gaps:	47/451 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 RKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLMMTLSKTADDATRDIRR 184
            :|.|:|| |.|..:: .|..:....|..:.::...:||:....:...:.....|..:::..::
  Fly    70 QKAIDAA-KQAYESK-EWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEV-- 130

  Fly   185 LLTSLRANADYLEHLSELRFEIQGDMNVFPS-------FHLRPMDGFVAALAPFE-SVALSSSLA 241
                ...|| ::|..:|....|.|:  :.||       ..::...|..|.:.|:. .:|:.:..|
  Fly   131 ----AYGNA-FVEWFAEEARRIYGE--IVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKA 188

  Fly   242 LCPALMGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSGVINFVPANERLFLDTI------TDAVHF 300
            ......|.||:..||.:....:..:.:...:||:|.||||.|..|:...:..:      ...:.|
  Fly   189 GAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISF 253

  Fly   301 AGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFA 365
            .| :|:.....:|:    .:|.::| ||.     |..|.....|..||.:|..|...:.:.|...
  Fly   254 TG-STEVGKLLFRN----SADGIKR-ICL-----ELGGNAPFIVFDSADIEKAVDGAMASKFRNC 307

  Fly   366 GQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETDIGAMVHINDFRRMQKLLQ--RTK 428
            ||...|.:|.:|..|::.:...:|.:..|.|.|||....:..||.:::...|.::...::  |:|
  Fly   308 GQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSK 372

  Fly   429 NMEQLCGGS-CDDSTGRFVDPTIVRVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSR 492
            ....:.||. ..|....|..||||....|...|..|...||.:.:..:.|:  .||:| .||.:|
  Fly   373 KANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDE--EEAVK-KANDTR 434

  Fly   493 YALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGLTPFGGNRLSGTNDKSGSAY 553
            ..|:|..::...:.:.....  |:....:.|||....:..  .||||.:.||.. :.||.:
  Fly   435 RGLAGYFYSENLQQVFRVAK--RLEVGMVGVNEGIISAAE--APFGGVKESGVG-REGSKH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	105/451 (23%)
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	105/451 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454114
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740