Protein Alignment CG6661 and aldh2.2

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_998466.2
• Gene: aldh2.2 / 368239
• ZFINID: ZDB-GENE-030326-5
• Length: 516
• Species: Danio rerio
• Alignment Length: 511
• Identity: 118/511 - (23%)
• Similarity: 210/511 - (41%)
• Gaps: 68/511 - (13%)

  Fly    61 PSIHRNQRVLVNHAIQEIQHRPLEVPTIIGDDTVYTMDTQRVCCPHHLQTNLAHVYYANRKQIEA 125
            |.:|.| ::.:|:...:...:. ..|||       ...|..:.|         ||...::..::.
Zfish    31 PDVHYN-KIFINNEWHDAVSKK-TFPTI-------NPATGEIIC---------HVAEGDKADVDK 77

  Fly   126 AIKSALSA---QGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLMMTLSKT-ADDATRDIRRLL 186
            |:|:|..|   ...|..:..:||..:..|.|..||.|...|.....:...|. |...:.|:..::
Zfish    78 AVKAARDAFKLGSPWRRMDASQRGLLLSRLADCIERDAAYLAELETLDNGKPYAVSFSVDVPMVV 142

  Fly   187 TSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVAALAPFESVALSSSLALCPAL-MGNT 250
            ..:|..|.:.:........|.|  |.|......|: |....:.|:....|..:..|.||| .|||
Zfish   143 KCMRYYAGWADKWEGKTIPIDG--NYFCYTRHEPI-GVCGQIIPWNFPLLMQAWKLGPALATGNT 204

  Fly   251 VLWNPSLEVAPVSYLIFRAFQEAGLPSGVINFVPANERLFLDTITDAVHFAGLNTQASAAFYRH- 314
            |:...:.:....:..|....:|.|.|:||:|.||                 |:...|.||...|
Zfish   205 VVMKVAEQTPLTALYIASLIKEVGFPAGVVNIVP-----------------GMGPTAGAAIASHM 252

  Fly   315 -VHKL----------VSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQY 368
             |.|:          :..|........::..|..|::.:.:.:.|.:|..|..:..|.|...||.
Zfish   253 DVDKVAFTGSTDVGHLIQRASSASNLKKVTLELGGKSPNIILSDANMEEAVEQSHIALFFNQGQC 317

  Fly   369 ANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETDIGAMVHINDFRRMQKLLQ--RTKNME 431
            ..:.:|.:|..|::....|..||..:...:|||.:..|:.|..|:.:.|:::...:.  :.:..:
Zfish   318 CCAGTRTFVQESIYDEFVERSVERAKNRIVGDPFDLNTEQGPQVNEDQFKKVLGYISSGKREGAK 382

  Fly   432 QLCGGSCDDSTGRFVDPTIV-RVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYAL 495
            .:|||:.....|.|:.||:. .|.|.: .:..|...||.:.:..:.  |..|.:: .||.|:|.|
Zfish   383 LMCGGAPAAERGYFIQPTVFGDVKDDM-TIAREEIFGPVMQILKFK--SLEEVIE-RANDSKYGL 443

  Fly   496 SGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGL-TPFGGNRLSGTNDKSG 550
            :|::|....:...:..:.||  |..:::|  |. :.:|: .||||.:.||...:.|
Zfish   444 AGAVFTQDIDKANYISHGLR--AGTVWIN--CY-NVFGVQAPFGGYKASGIGREMG 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	115/504 (23%)
aldh2.2	NP_998466.2	ALDH_F1AB_F2_RALDH1	30..510	CDD:143459	118/511 (23%)