DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6661 and CG31076

DIOPT Version :9

Sequence 1:	NP_648686.3	Gene:	CG6661 / 39556	FlyBaseID:	FBgn0036403	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_733184.2	Gene:	CG31076 / 318582	FlyBaseID:	FBgn0051076	Length:	182	Species:	Drosophila melanogaster

Alignment Length:	189	Identity:	35/189 - (18%)
Similarity:	61/189 - (32%)	Gaps:	75/189 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 RDIRRLLTSL-RANADYLEHL----------------SELRFEIQGDMNVFPSFHLRPMDGFVAA 227
            :::|.|...| :.:||::|.|                .:||..:. |.|.....|||.:
  Fly    16 QNLRTLPQELVKKHADHVEQLDLSHNCLKDLSWLADFEQLRHLVL-DSNRMHEAHLRTL------ 73

  Fly   228 LAPFESVALSSSLALCPALMGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSG---VINFVPANERL 289
                          .||.         |.|||     |:....:.:.||:.   :..|.|..:
  Fly    74 --------------TCPL---------PQLEV-----LMLNKNEFSDLPTTMRLIRKFFPNLQ-- 108

  Fly   290 FLDTITDAVHFAGLNTQASAAFYRHVHKLVSD------------------RMERYICFP 330
            :|....:.:...||..|..:.:.|:.::..|:                  |..:|..||
  Fly   109 YLSLHGNPICPDGLELQPFSTYLRYDYEYYSNYIAQSLSKLKFLDHGLVQRTYKYESFP 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	35/189 (19%)
CG31076	NP_733184.2	LRR_8	11..65	CDD:290566	11/49 (22%)
		leucine-rich repeat	11..32	CDD:275378	4/15 (27%)
		leucine-rich repeat	33..54	CDD:275378	2/20 (10%)
		leucine-rich repeat	55..79	CDD:275378	9/53 (17%)
		leucine-rich repeat	80..106	CDD:275378	7/30 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900