Protein Alignment CG6661 and Aldh1a3

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_695212.2
• Gene: Aldh1a3 / 266603
• RGDID: 628662
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 134/563 - (23%)
• Similarity: 226/563 - (40%)
• Gaps: 102/563 - (18%)

  Fly    51 EPDSQPAEENPSIHRNQRVLVNHAIQEIQHRPLEVPTIIGDD----------TVYTMDT-QRVCC 104
            :||.:|    |::.|..|.|      |::...:    .|.:|          ..|...| :::|
  Rat    12 QPDGKP----PALPRPIRNL------EVKFTKI----FINNDWHESKSGRKFATYNPSTLEKIC- 61

  Fly   105 PHHLQTNLAHVYYANRKQIEAAIKSALSA--QGT-WSLVPIAQRLAIWRRAATIIEEDELRLRVF 166
                     .|...::..::.|:::|.:|  :|: |..:....|..:..:.|.:||.|..
  Rat    62 ---------EVEEGDKPDVDKAVEAAQAAFQRGSPWRRLDALSRGQLLHQLADLIERDRA----- 112

  Fly   167 LMMTLSKTADDATRDIRRLLTSLRANADYLEHLSELRFEIQG-----DMNVFPSFHLRPMDGFVA 226
            ::.|| :|.|.....:......|........:.:....:|||     |.||.......|: |...
  Rat   113 ILATL-ETMDTGKPFLHAFFVDLEGCIKTFRYFAGWADKIQGRTIPTDDNVMCFTRHEPI-GVCG 175

  Fly   227 ALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYLIFRA-FQEAGLPSGVINFVPANERL 289
            |:.|:....|..:..|.||| .||||:..|: |..|::.|...: .:|.|.|.||:|.||
  Rat   176 AITPWNFPLLMLAWKLAPALCCGNTVVLKPA-EQTPLTALYLASLIKEVGFPPGVVNIVP----- 234

  Fly   290 FLDTITDAVHFAGLNTQASAAFYRH-------------VHKLVSDRMERYICFPRLVAECPGQNF 341
                        |......||...|             |.|||.:...| ....|:..|..|:|.
  Rat   235 ------------GFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR-SNLKRVTLELGGRNP 286

  Fly   342 HFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESET 406
            ..|.|.|.::..|....|..|...||...:.||::|...::.......||..::..:|||.:::|
  Rat   287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYGEFVRRSVEFAKKRPVGDPFDAKT 351

  Fly   407 DIGAMVHINDFRRMQKLLQRTK----NMEQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLC--EPC 465
            :.|..:....|.::.:|::..|    .:|  ||||..:..|.|:.||:  .||..|.:..  |..
  Rat   352 EQGPQIDQKQFDKILELIESGKKEGAKLE--CGGSAMEDRGLFIKPTV--FSDVTDNMRIAKEEI 412

  Fly   466 CGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGS 530
            .||..|:..:.  :..|.:| .||.:.|.|:.::|....:..|...:.|  .:..::||  |..:
  Rat   413 FGPVQPILKFK--NLEEVIK-RANSTDYGLTAAVFTKNLDKALKLASAL--ESGTVWVN--CYNA 470

  Fly   531 TYGLTPFGGNRLSGTNDKSGSAYFLMRWSSPLLIEETVDGPPP 573
            .|...||||.::||...:.|. |.|..::....:...:|...|
  Rat   471 FYAQAPFGGFKMSGNGRELGE-YALAEYTEVKTVTIKLDEKNP 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	127/538 (24%)
Aldh1a3	NP_695212.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		4/14 (29%)
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	126/537 (23%)