DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6661 and Aldh3a1

DIOPT Version :9

Sequence 1:	NP_648686.3	Gene:	CG6661 / 39556	FlyBaseID:	FBgn0036403	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_114178.1	Gene:	Aldh3a1 / 25375	RGDID:	2088	Length:	453	Species:	Rattus norvegicus

Alignment Length:	453	Identity:	100/453 - (22%)
Similarity:	179/453 - (39%)	Gaps:	90/453 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 NRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVFLMMTLSKTADDATRDIR 183
            |.|.|..|:.|.| .:..|:        :.:...|.::||         :.|..|...|...|
  Rat    40 NLKSISGALASDL-GKNEWT--------SYYEEVAHVLEE---------LDTTIKELPDWAED-- 84

  Fly   184 RLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVAALA----PFESVALSSSLALCP 244
                         |.:::.|...|.|:.:    |..|: |.|..:.    ||       :|.:.|
  Rat    85 -------------EPVAKTRQTQQDDLYI----HSEPL-GVVLVIGAWNYPF-------NLTIQP 124

  Fly   245 AL----MGNTVLWNPSLEV----APVSYLIFRAFQEAGLPSGVINFVPANERLFLDTITDAVHFA 301
            .:    .||.|:..|| ||    |.:...:...:.:..|...|...||....|..:.. |.:.:.
  Rat   125 MVGAVAAGNAVILKPS-EVSGHMADLLATLIPQYMDQNLYLVVKGGVPETTELLKERF-DHIMYT 187

  Fly   302 GLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFAG 366
            |     |.|    |.|:|.....:::  ..:..|..|::..:|.....::   .|..:.|:   |
  Rat   188 G-----STA----VGKIVMAAAAKHL--TPVTLELGGKSPCYVDKDCDLD---VACRRIAW---G 235

  Fly   367 QYANSLSRMYVPSSMW--PRLREELVEATEQLT---IGDPIESETDIGAMVHINDFRRMQKLLQR 426
            ::.||......|..:.  |.::.::||..::..   .|:..:...|.|.:::...|:|::.|:.
  Rat   236 KFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLID- 299

  Fly   427 TKNMEQLCGGSCDDSTGRFVDPTIVRVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQS 491
              |.:...||:.|.|: |::.|||:...||..|::.|...||.:|:....  |..||::. .||.
  Rat   300 --NQKVAHGGTWDQSS-RYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVR--SLEEAIQF-INQR 358

  Fly   492 RYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGLTPFGGNRLSGTNDKSGSAYF 554
            ...|:..:|::.::||...:.:  .|:..:..|:.....|....||||...||.....|...|
  Rat   359 EKPLALYVFSNNEKVIKKMIAE--TSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSF 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	100/453 (22%)
Aldh3a1	NP_114178.1	ALDH_F3AB	5..447	CDD:143450	100/453 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900