Protein Alignment CG6661 and Aldh8a1

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_848828.1
• Gene: Aldh8a1 / 237320
• MGIID: 2653900
• Length: 487
• Species: Mus musculus
• Alignment Length: 477
• Identity: 123/477 - (25%)
• Similarity: 201/477 - (42%)
• Gaps: 67/477 - (14%)

  Fly    95 YTMDTQRVCCPHHLQTNLAHVYYANRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATIIEED 159
            |...|..|.|         .|..:.:::||||:::|..|...||.....:|..:..|.|.::|:.
Mouse    28 YDPSTGEVYC---------KVPNSGKEEIEAAVEAAREAFPAWSSRSPQERSLVLNRLADVLEQS 83

  Fly   160 ELRLRVFLMMTLSKTADDA-TRDIRRLLTSLRANA-DYLEHLSE-LRFEIQGDMNVFPSFHLRPM 221
            ...|.........||...| |.||.|.:.:.|..| ..|.|:|| .:....|.|:    :.:|..
Mouse    84 LEELAQAESKDQGKTLTLARTMDIPRSVLNFRFFASSNLHHVSECTQMSHLGCMH----YTVRTP 144

  Fly   222 DGFVAALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSGVINFV-- 283
            .|....::|:.......:..:.||: .||||:..||...:..:::..:...:||:|.||||.|
Mouse   145 VGIAGLISPWNLPLYLLTWKIAPAIAAGNTVIAKPSEMTSVTAWMFCKLLDKAGVPPGVINIVFG 209

  Fly   284 ---PANERLFLDTITDAVHFAGLN------TQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQ 339
               ...|.|........:.|.|..      ||.||.   |..|              |..|..|:
Mouse   210 TGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP---HCKK--------------LSLELGGK 257

  Fly   340 NFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIES 404
            |...:...|.:|..:.|||:::|...|:.....||::|..|::....:..||||.:..:|.|.:.
Mouse   258 NPAIIFEDANLEECIPATVRSSFANQGEICLCTSRIFVQRSIYSEFLKRFVEATRKWKVGVPSDP 322

  Fly   405 ETDIGAMV---HINDFRRMQKLLQRTKNMEQLCGGSCD-------DSTGRFVDPTIVRVSDPLDP 459
            ..::||::   |:... |...|..:|:....|||...|       :..|.|:.||:  ::|..|.
Mouse   323 SANMGALISKAHLEKV-RSYVLKAQTEGARILCGEGVDQLSLPLRNQAGYFMLPTV--ITDIKDE 384

  Fly   460 LLC--EPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLY 522
            ..|  |...||...|..:  ||..|.: ..||..||.|:.::: |:|...:|.:.: ::.:..::
Mouse   385 SRCMTEEIFGPVTCVVPF--DSEEEVI-TRANSVRYGLAATVW-SKDVGRIHRVAK-KLQSGLVW 444

  Fly   523 VNERCTGSTYGLTPFGGNRLSG 544
            .|  |........||||.:.||
Mouse   445 TN--CWLIRELNLPFGGMKSSG 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	123/477 (26%)
Aldh8a1	NP_848828.1	ALDH_F8_HMSADH	27..485	CDD:143412	123/477 (26%)