Protein Alignment CG6661 and ALDH1A3

DIOPT Version :9

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_000684.2
• Gene: ALDH1A3 / 220
• HGNCID: 409
• Length: 512
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 121/485 - (24%)
• Similarity: 202/485 - (41%)
• Gaps: 67/485 - (13%)

  Fly   104 CPHHLQTNLAHVYYANRKQIEAAIKSALSA--QGT-WSLVPIAQRLAIWRRAATIIEEDELRLRV 165
            |....:..:..|...::..::.|:::|..|  :|: |..:....|..:..:.|.::|.|...|..
Human    52 CNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAA 116

  Fly   166 FLMMTLSKTADDA-TRDIRRLLTSLRANADYLEHLSELRFEIQG-----DMNVFPSFHLRPMDGF 224
            ...|...|....| ..|:...:.:||..|.:.:       :|||     |.||.......|: |.
Human   117 LETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD-------KIQGKTIPTDDNVVCFTRHEPI-GV 173

  Fly   225 VAALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYLIFRA-FQEAGLPSGVINFVPANE 287
            ..|:.|:....|.....|.||| .|||::..|: |..|::.|...: .:|||.|.||:|.||
Human   174 CGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA-EQTPLTALYLGSLIKEAGFPPGVVNIVP--- 234

  Fly   288 RLFLDTITDAVHFAGLNTQASAAFYRH-------------VHKLVSDRMERYICFPRLVAECPGQ 339
                          |......||...|             |.|||.:...| ....|:..|..|:
Human   235 --------------GFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR-SNLKRVTLELGGK 284

  Fly   340 NFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIES 404
            |...|.|.|.::..|....|..|...||...:.||::|...::.......||..::..:|||.:.
Human   285 NPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDV 349

  Fly   405 ETDIGAMVHINDFRRMQKLLQRTK----NMEQLCGGSCDDSTGRFVDPTIV-RVSDPLDPLLCEP 464
            :|:.|..:....|.::.:|::..|    .:|  ||||..:..|.|:.||:. .|:|.: .:..|.
Human   350 KTEQGPQIDQKQFDKILELIESGKKEGAKLE--CGGSAMEDKGLFIKPTVFSEVTDNM-RIAKEE 411

  Fly   465 CCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTG 529
            ..||..|:..:.  |..|.:| .||.:.|.|:.::|....:..|...:.|  .:..:::|  |..
Human   412 IFGPVQPILKFK--SIEEVIK-RANSTDYGLTAAVFTKNLDKALKLASAL--ESGTVWIN--CYN 469

  Fly   530 STYGLTPFGGNRLSGTNDKSGSAYFLMRWS 559
            :.|...||||.::||...:.|. |.|..::
Human   470 ALYAQAPFGGFKMSGNGRELGE-YALAEYT 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	121/485 (25%)
ALDH1A3	NP_000684.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	121/485 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810