Protein Alignment CG6661 and Aldh4a1

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_780647.3
• Gene: Aldh4a1 / 212647
• MGIID: 2443883
• Length: 562
• Species: Mus musculus
• Alignment Length: 513
• Identity: 190/513 - (37%)
• Similarity: 303/513 - (59%)
• Gaps: 20/513 - (3%)

  Fly    67 QRVLVNHAIQEIQHRPLEVPTIIGDDTVYTMDTQRVCCPHHLQTNLAHVYYANRKQIEAAIKSAL 131
            :|..:..|:::::.:...:|.::||:.|:|.|.|....|.:....:|...||::..:..||.:||
Mouse    45 ERDALQKALKDLKGQMEAIPCVVGDEEVWTSDIQYQLSPFNHAHKVAKFCYADKALLNRAIDAAL 109

  Fly   132 SAQGTWSLVPIAQRLAIWRRAATIIEEDELRLRVF--LMMTLSKTADDATRD-IRRLLTSLRANA 193
            :|:..|.|.|:|.|..::.:||.::.... |..|.  .|:...||...|..| ...|:...|.||
Mouse   110 AARKEWDLKPMADRAQVFLKAADMLSGPR-RAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNA 173

  Fly   194 DYLEHLSELRFEIQGD--MNVFPSFH---LRPMDGFVAALAPFESVALSSSLALCPALMGNTVLW 253
            .:       ..|::|:  ::|.||.:   .|.::|||||::||...|:..:||..||||||.|||
Mouse   174 KF-------AVELEGEQPISVPPSTNHTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLW 231

  Fly   254 NPSLEVAPVSYLIFRAFQEAGLPSGVINFVPANERLFLDTITDAVHFAGLNTQASAAFYRHVHKL 318
            .||......||.::|..:|||||..:|.||||:...|.||:|.:.|..|:|...|...::|:.:.
Mouse   232 KPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQ 296

  Fly   319 VSDRMERYICFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWP 383
            |:..::|:..||||..||.|:||||||:||.|:||||.|:::||.:.||..::.||:|||.|:||
Mouse   297 VAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWP 361

  Fly   384 RLREELVEATEQLTIGDPIES-ETDIGAMVHINDFRRMQKLLQRTK---NMEQLCGGSCDDSTGR 444
            :::..|:|...::.:|||.|. .|...|::....|.|::|.|:..:   ::..|.||.|::|.|.
Mouse   362 QIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGY 426

  Fly   445 FVDPTIVRVSDPLDPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILH 509
            :|:|.|:...||.:|::.|...||.|.|:||.||.:.|.|:|..:.:.|.|:|::||....::..
Mouse   427 YVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLQLVDSTTSYGLTGAVFAQDKAIVQE 491

  Fly   510 CLNQLRMSASNLYVNERCTGSTYGLTPFGGNRLSGTNDKSGSAYFLMRWSSPLLIEET 567
            ....||.:|.|.|:|::.|||..|..||||.|.||||||.|..::::||:||.:|:||
Mouse   492 ATRMLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKET 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	188/510 (37%)
Aldh4a1	NP_780647.3	ALDH_F4-17_P5CDH	31..552	CDD:143441	190/513 (37%)