Protein Alignment CG6661 and Aldh1a2

DIOPT Version :10

• Sequence 1: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_033048.2
• Gene: Aldh1a2 / 19378
• MGIID: 107928
• Length: 518
• Species: Mus musculus
• Alignment Length: 498
• Identity: 117/498 - (23%)
• Similarity: 209/498 - (41%)
• Gaps: 58/498 - (11%)

  Fly   102 VCCPHHLQTNLAHVYYANRKQIEAAIKS---ALSAQGTWSLVPIAQRLAIWRRAATIIEEDELRL 163
            ||.| .....:..|..|::..|:.|:::   |.|....|..:..::|..:..:.|.::|.|...|
Mouse    57 VCNP-ATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATL 120

  Fly   164 RVFLMMTLSKTADDATR-DIRRLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPMDGFVAA 227
            .....:...|....|.. |::.::.:||..|.:.:.:..:...:.||...|...  .|: |....
Mouse   121 ATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRH--EPI-GVCGQ 182

  Fly   228 LAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYLIFRA-FQEAGLPSGVINFVPANERLF 290
            :.|:....|..:..:.||| .||||:..|: |..|:|.|...| .:|||.|.||:|.:|
Mouse   183 IIPWNFPLLMFTWKIAPALCCGNTVVIKPA-EQTPLSALYMGALIKEAGFPPGVVNILP------ 240

  Fly   291 LDTITDAVHFAGLNTQASAAFYRH-------------VHKLVSDRMERYICFPRLVAECPGQNFH 342
                       |....|.||...|             |.||:.:...| ....|:..|..|::.:
Mouse   241 -----------GYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR-SNLKRVTLELGGKSPN 293

  Fly   343 FVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETD 407
            .:.|.|.::..|....|..|...||...:.||::|..|::....:..||..::..:|.|.:..|:
Mouse   294 IIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTE 358

  Fly   408 IGAMVHINDFRRMQKLLQR--TKNMEQLCGGSCDDSTGRFVDPTIV-RVSDPLDPLLCEPCCGPF 469
            .|..:....:.::.:|:|.  .:..:..|||......|.|::||:. .|:|.: .:..|...||.
Mouse   359 QGPQIDKKQYNKVLELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDM-RIAKEEIFGPV 422

  Fly   470 LPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTGSTYGL 534
            ..:..:.  :..|.:: .||.|.:.|..::|.:.....|  :....|.|..:::|  |..:....
Mouse   423 QEILRFK--TMDEVIE-RANNSDFGLVAAVFTNDINKAL--MVSSAMQAGTVWIN--CYNALNAQ 480

  Fly   535 TPFGGNRLSGTNDKSGSAYFLMRWSSPLLIEETVDGPPPMRGS 577
            :||||.::||...:.|.  |.:|..|.:   :||....|.:.|
Mouse   481 SPFGGFKMSGNGREMGE--FGLREYSEV---KTVTVKIPQKNS 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	113/486 (23%)
Aldh1a2	NP_033048.2	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	115/490 (23%)