DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6661 and aldh9a1a.1

DIOPT Version :9

Sequence 1:	NP_648686.3	Gene:	CG6661 / 39556	FlyBaseID:	FBgn0036403	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_958879.1	Gene:	aldh9a1a.1 / 100005587	ZFINID:	ZDB-GENE-030131-1257	Length:	508	Species:	Danio rerio

Alignment Length:	483	Identity:	116/483 - (24%)
Similarity:	205/483 - (42%)	Gaps:	63/483 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 DTVYTMDTQRVCCPHHLQTNLAHVYYANRKQIEAAIKSALSAQGTWSLVPIAQRLAIWRRAATII 156
            :.||...|.||.|         .:.....::::.|||||.||...||.:...:|..|...||.||
Zfish    43 EPVYEPATGRVLC---------DMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARII 98

  Fly   157 EEDELRLRVFLMMTLSKTADDATRDIRRLLTSLRANADYLEHLSELRFEIQGDMNVFPSFHLRPM 221
            .|....:....:....|:..:|..||......:...|.....||....::.|  ..|......|:
Zfish    99 RERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPG--GSFAYTRREPL 161

  Fly   222 D---GFVAALAPFESVALSSSLALCPALMGNTVLWNPSLEVAPVSYLIFRAFQEAGLPSGVINFV 283
            .   |..|...||:..|..|:.||.   .||.:::.||......:.::...::|||:|.|:.|.|
Zfish   162 GVCVGIGAWNYPFQIAAWKSAPALA---CGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVV 223

  Fly   284 PANER----LFLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFV 344
            .....    |....:...|.|.|     |....:.|.::.:..::      ::..|..|::...:
Zfish   224 QGGAETGSLLCHHPMVAKVSFTG-----SVPTGKKVMEMAAKSVK------QVTLELGGKSPLII 277

  Fly   345 HASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIESETDIG 409
            ....::|:.:...:.|.|...|:...:.:|::|...:.|:..||:|:.|:.:::|||:...|.:|
Zfish   278 FKDCELENAIKGALMANFLTQGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMG 342

  Fly   410 AMV---HINDFRRMQKLLQRTKNMEQ-----LCGGS---CDD---STGRFVDPTIVRVSDPLDPL 460
            |::   |      |:|:|...|..::     ||||.   .:|   ..|.||.|.:  :.:..|.:
Zfish   343 ALISKPH------MEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCV--LDNCRDDM 399

  Fly   461 LC--EPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYV 523
            .|  |...||.:.|..:  |:..|.|: .||.:.:.|:..:| ::|....|.: ...:.|...|:
Zfish   400 TCVKEEIFGPVMSVLPF--DTEEEVLQ-RANNTTFGLASGVF-TRDIARAHRV-AANLQAGTCYI 459

  Fly   524 NERCTGSTYGLTPFGGNRLSGTNDKSGS 551
            |....|...  .||||.::||...::|:
Zfish   460 NNYNVGPVE--VPFGGYKMSGFGRENGT 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:299846	116/483 (24%)
aldh9a1a.1	NP_958879.1	ALDH_F9_TMBADH	45..502	CDD:143409	116/481 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810