Protein Alignment Ptip and Ect2

DIOPT Version :9

• Sequence 1: NP_729947.2
• Gene: Ptip / 39552
• FlyBaseID: FBgn0052133
• Length: 2294
• Species: Drosophila melanogaster
• Sequence 2: NP_001102017.2
• Gene: Ect2 / 361921
• RGDID: 1308524
• Length: 913
• Species: Rattus norvegicus
• Alignment Length: 553
• Identity: 84/553 - (15%)
• Similarity: 179/553 - (32%)
• Gaps: 205/553 - (37%)

  Fly     5 KISDKLFEDVIYFVLGNLD--------EEIERFLKSGGAQSKLFLSDQITHMICATNYNEEELSM 61
            |..:||.:.:|     |::        :.:|.|   |...|..|     .::...|::   :.|:
  Rat    89 KSDEKLIKSII-----NMEIKVPCVKMDSMEEF---GSLDSPEF-----ENIFVVTDF---QTSV 137

  Fly    62 NLDLYSA------IPVTEQWIVHSAKLGRMASTRAFDPSPNQMRLMRGIRVAITNVV---AGDRR 117
            ..|||.|      .||    |::.|::|        :|.|...|.:  ...::.|:|   .|.|:
  Rat   138 FNDLYKADCRIVGPPV----ILNCAQMG--------EPLPFSCRPL--YCTSMLNLVLCFTGFRK 188

  Fly   118 -----RLYAMLTYHGAVVTHSFGATNTHLVCGAANGGIYNKALALPKNAIIIVTPDWVTDSLKYK 177
                 :|..::.:.|.|:.....:..||||.....|..:..|::|   ...|:.|.|:.::.:.:
  Rat   189 KEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSL---GTPIMRPGWIYEAWERR 250

  Fly   178 NCMPVETYHPRLLKPIEKQRTQKQQATQQQQIQQQQQLQHQHQMQQQQQQQQQQQQQQQQQQQQQ 242
            |                          :|.........:::.::...|
  Rat   251 N--------------------------EQCFCAADDDFRNEFKVPPFQ----------------- 272

  Fly   243 QQQQQQQQQQQQQQHQQQIIQQQATATSALSDILGFGEDSVAAKSIASIKSQLQASAEQIQQQQ- 306
                                       ..:...|||.::.             :.|.|::.:.|
  Rat   273 ---------------------------DCILSFLGFSDEE-------------KHSMEEMTEMQG 297

  Fly   307 ---LPVPAQQQV-VFVRPQPQPQQPAQQSPHQLQQGGPQAPTPAPHPQHQQQLIIQQQKIIPANL 367
               |||..::.. :.|......:.|.:.|                     ::|.:.:|:....::
  Rat   298 GTYLPVGDERCTHLIVDENTVKELPFEPS---------------------KKLFVVKQEWFWGSI 341

  Fly   368 QQ-----------QPQNQQQIKNILQQRQMKTTQQSQQQQQIQMQLMQ--QEQQPHPQPLQQQLA 419
            |.           :..|..::|..:....:.|...::::::::..|.|  :|....|.|.:::.:
  Rat   342 QMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRRLKESLAQLSRETDLSPFPPRKRPS 406

  Fly   420 QQHPQQIAQQLPQQLSQQHPQQIPQQQQSPRLPTTPTGR----QTPR-----TPSTTPQPVQSPQ 475
            .:|...|...|.                   :..||...    :||:     :.|:||.|.:...
  Rat   407 AEHSLSIGSLLD-------------------ISNTPDSSIHYGETPKSCAKSSRSSTPVPPKQSA 452

  Fly   476 HHQQIVQQQQVVQQQVGQQQTMVQQQQIVQQQQ 508
            ..|...:..|.....|....|::|..|:..:::
  Rat   453 RWQVAKELYQTESNYVNILATIIQLFQVPLEEE 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptip	NP_729947.2	BRCT	9..77	CDD:214602	17/81 (21%)
		BRCT	96..174	CDD:278934	18/85 (21%)
		BRCT	1814..1887	CDD:237994
		PTCB-BRCT	1914..1976	CDD:289507
		BRCT	<2087..2142	CDD:237994
		BRCT	2175..2265	CDD:278934
Ect2	NP_001102017.2	PTCB-BRCT	179..242	CDD:289507	15/65 (23%)
		BRCT	266..341	CDD:278934	15/152 (10%)
		RhoGEF	456..640	CDD:279015	5/30 (17%)
		PH_Ect2	631..804	CDD:269936

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D305707at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010