Protein Alignment upSET and SET3

DIOPT Version :9

• Sequence 1: NP_001261819.1
• Gene: upSET / 39551
• FlyBaseID: FBgn0036398
• Length: 3146
• Species: Drosophila melanogaster
• Sequence 2: NP_012954.3
• Gene: SET3 / 853900
• SGDID: S000001737
• Length: 751
• Species: Saccharomyces cerevisiae
• Alignment Length: 493
• Identity: 102/493 - (20%)
• Similarity: 156/493 - (31%)
• Gaps: 202/493 - (40%)

  Fly   818 AHSAISSSSRMGL------------ASTDIDPGEETETAPEAEAE-----------DDSVTRCIC 859
            |.:|::::|.:.|            |:|.....||||..|:.:.:           |..:..|||
Yeast    58 AAAALATASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQWPVPDSYIVDPDAGIITCIC 122

  Fly   860 ELTHDDGYMICCDKCSAWQHVDCMGI-DRQNIPEEYMCELCQPRAVDKARARALQRQKRKEHMLL 923
            :|..|||:.|.||.|:.|||..|.|| |....|::|:|..|.||.||...||.:|::  :.::..
Yeast   123 DLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQE--RINVKT 185

  Fly   924 VATQAANGAAA-------VAAGTTLSGGLGSGLPMSEELQHRLASGLNGGFATGTGMSKKSKKTK 981
            |...::|.:|:       .|:.||:|....|.....:...||                  .|:.|
Yeast   186 VEPSSSNNSASNKNNGRDRASSTTISDVGDSFSTDQDNTNHR------------------DKRRK 232

  Fly   982 ENSGSTSTLKKTKKSAVGMGGEKNASGSGTPTGSSGKTSKKSSKRKSKSGGDGSSGGGS------ 1040
            .|..:.|...|.:.::|              ..|.|.||....|....|..|..   |:
Yeast   233 RNPSNNSIDSKNESASV--------------NSSDGLTSMPKKKEHFLSAKDAY---GAIYLPLK 280

  Fly  1041 ---------SPALTAAEKHAANLRQWIENYEYAVTNHYSPELRARLHAIQKQPSLLQSIQNTENK 1096
                     .|.|   .||..:  .|:..|.:......|.|::
Yeast   281 DNVFKSDLIEPFL---NKHMDD--NWVIQYPHKTFKSVSIEVK---------------------- 318

  Fly  1097 ALRQIQQQLSTAGSAEQLEQRAQLIPYAGAKVLISSVDLSPHAP------------------IHE 1143
                                     |||       .:..|...|                  |.|
Yeast   319 -------------------------PYA-------DIAYSRTYPGFTKLGVYLKKDCIKGDFIQE 351

  Fly  1144 LRGKYMLTTQFRTQNPTVNMNTPPPSNYLNSFKAHKTPGQFVFFYQLPGVEAPMQTLRPDGSVPQ 1208
            :.|:......:.|.          |.|:   ::...|..:.|.|:
Yeast   352 ILGELDFYKNYLTD----------PRNH---YRIWGTAKRRVIFH-------------------- 383

  Fly  1209 VAQQPPSYLKGPEVCVDTRTYGNDARFVRRSCRPNAEL 1246
              ...|.|       :|.|..||..|::||||:||.||
Yeast   384 --SHWPIY-------IDARLSGNSTRYLRRSCQPNVEL 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
upSET	NP_001261819.1	PHD_MLL5	856..899	CDD:277025	21/43 (49%)
		SET	<1221..1273	CDD:214614	13/26 (50%)
SET3	NP_012954.3	PHD_MLL5	119..163	CDD:277025	21/43 (49%)
		SET	217..722	CDD:225491	53/332 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346292
Domainoid	1	1.000	58	1.000	Domainoid score	I2633
eggNOG	1	0.900	-	-		E1_KOG1844
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46856
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46462
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.960