Protein Alignment Nprl3 and NPR3

DIOPT Version :9

• Sequence 1: NP_001261818.1
• Gene: Nprl3 / 39550
• FlyBaseID: FBgn0036397
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_011840.1
• Gene: NPR3 / 856362
• SGDID: S000001015
• Length: 1146
• Species: Saccharomyces cerevisiae
• Alignment Length: 788
• Identity: 134/788 - (17%)
• Similarity: 235/788 - (29%)
• Gaps: 331/788 - (42%)

  Fly    42 RKSRKRNPYAVANTDDLLQTPTHLGAAK---------SQGQLQ----GFADEVLSALFA------ 87
            |||:.:|......:.   .|.|::...|         |:..|:    |.||.|..:...
Yeast   443 RKSKHKNKTRSKRSS---STTTNISRKKSIASKISSLSENTLKKVNSGEADTVYDSNIGHEASTD 504

  Fly    88 -----VKPQLCNQKFELKLND---------VRFVSHPTLIPQKEQRSGPMAKQQMLINIVFALHA 138
                 :...:...:||.:..|         |.||.:|.||...::
Yeast   505 TPNLRINTDVSGNEFEREKEDLGKNMNMFHVCFVMNPHLIEYNKR-------------------- 549

  Fly   139 QASYSIVKCYHELSKRLGLALKFEEQRSGYLTEQ----------------TAQMARTHDEQQQQP 187
                 |...|..:..||.|.|::.:.::.|::.:                |.|..|....:.:..
Yeast   550 -----IDDMYQFVVTRLSLLLRYVQSKTSYISSECHIILKEKERVLKHSKTYQSIRGAGNKGKYL 609

  Fly   188 LERTLELIAERCSLAQALRSIFHDLCTTGLLSTSLNHNLTLCFCLPAK----------------- 235
            .:|    |..:.|||:||......:....:....:|.:..:...:|.:
Yeast   610 YQR----ILAKSSLARALTECVDKIQRNEIACLEINDDKVISLQIPIQNEFEKMPNFKLQPVLRG 670

  Fly   236 ----------------------------------AHQLHKKGSMVDPETIDRCLRA--------- 257
                                              .:.:::.|:.::  :...|..|
Yeast   671 SYLTSILNMKFLEKSSLRIESQNRQNDQAQFSDTNNNIYRFGNNIN--STGHCGAANVDDGDDNE 733

  Fly   258 ----------LKPYHGMLL-----LVDFAELLDCVPPTGARMLWQLVDVYDPLISLQSM------ 301
                      |..|..:||     ::...|........|..:|..||....|.|.|:|.
Yeast   734 SNYYCDDNDDLLNYALLLLDEPNNIISSLETFSYQDDIGTIILKHLVRNIQPNIPLRSYRYLITD 798

  Fly   302 -----SSNADLSIEH-------VYKLVSHLVYWAKATIIYPLCETNVYVIAPDAPLH-------- 346
                 ||..||:.|.       :.....||:||..|.|:.||.....|:::|.||:.
Yeast   799 LLDNPSSLDDLTTETNSLESSILRSCALHLMYWRHARIVIPLSSKYTYIVSPLAPIQGYTIDDYK 863

  Fly   347 ---TKSHLVEKFSAR-------------FAGMSLFEVISDF----SLPTSIGHLTTPLQQ----- 386
               .....|:|...|             :....||.  |.|    |||..:..|:|...|
Yeast   864 STSQNDGNVKKMDDRENNKSGSDRVPLIYQNSMLFR--SKFPSLPSLPIFLSLLSTDKPQAYSNI 926

  Fly   387 -PARQ--GILAQMVIWMLQHHLLMQLHTYVQFMPSEDEFGDSASCSNHLRDAISDEEGDQEPDAD 448
             |:|:  .:....:.|::|:..:.||.|::           :.....|::.|: ||:.::|
Yeast   927 IPSREHKPVYLNALAWLIQYGYVTQLLTFI-----------NIRVDKHIKMAV-DEDLEKE---- 975

  Fly   449 ELHGSMLSMSSHPLPVPAVLVGGHRREASEDHSSLASDNIAVQPSSSHK---------------S 498
                                  |.|:           .|.|.:||..:|               :
Yeast   976 ----------------------GFRK-----------TNTARRPSMDYKKTDKKLDDEDGQSRDA 1007

  Fly   499 NFSITAS------MSTDNCDSLDSMEDEQKLK---------------ELLQ-------------V 529
            |.|...|      .|.||...:|..::|...:               |:|.             :
Yeast  1008 NASEACSGKNEGMQSNDNNKDVDEKDNENDSRVDDRDDNEIAIADEEEILHFEYDDPEMQHDYTI 1072

  Fly   530 FSDADRA-AIRR---------IPASANVDDLSLLVKLYQMGYFKSEHHLEEIMYFENLRR---SQ 581
            ..:.:|| ||.:         .|:...:    |..||  :.||..:..:|.::..|.:.|   .:
Yeast  1073 ILEPERATAIEKRWLYRCIYGQPSDIQI----LFNKL--LKYFNGKVPMELVIIKEEISRHDLKK 1131

  Fly   582 LLQLLDKF 589
            ||..|||:
Yeast  1132 LLNALDKY 1139

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nprl3	NP_001261818.1	NPR3	76..413	CDD:305178	85/501 (17%)
NPR3	NP_011840.1	NPR3	400..966	CDD:397640	95/569 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006449
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104131
Panther	1	1.100	-	-	LDO	PTHR13153
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R838
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960