Protein Alignment Nprl3 and SPBC543.04

DIOPT Version :9

• Sequence 1: NP_001261818.1
• Gene: Nprl3 / 39550
• FlyBaseID: FBgn0036397
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001342971.1
• Gene: SPBC543.04 / 2541073
• PomBaseID: SPBC543.04
• Length: 585
• Species: Schizosaccharomyces pombe
• Alignment Length: 670
• Identity: 127/670 - (18%)
• Similarity: 246/670 - (36%)
• Gaps: 181/670 - (27%)

  Fly     8 LAVILVYFDSKGDRLLYRYPYQ-----------------TLGQTEVANDEQRKSRKRNPYAVANT 55
            :|:.||...:.|...::.:|.|                 .:|..::.:.:..::.:....|
pombe     9 VAIFLVEKTTSGANFVFHWPLQPQVRLQATHHNNDSAESAIGMLDLDDSDDDENNRFTEVA---- 69

  Fly    56 DDLLQTPTHLGAAKSQGQLQGFADEVLSALFAVKPQLCNQKFELKLNDVRFV------------- 107
            ||     ||:     .|..:||...:||.    :.:|||||||:.::.:.|:
pombe    70 DD-----THV-----LGYEKGFLANMLSP----RIELCNQKFEIWVDGLTFLGCPVHIGPNGEWA 120

  Fly   108 ------------------------SHPTLIPQKEQRSGPMAKQQM-LINIVFALHAQASY----S 143
                                    |||:....:.:.|...::..| |.::||.|:...:.    :
pombe   121 KRRKPRTTVESNASSSHLVSKPESSHPSTGSFEVKSSSSKSRSSMSLFHVVFVLNVPTATVYRPT 185

  Fly   144 IVKCYHELSKRLGLALKFEEQRSGYLTEQTAQMARTHDEQQQQ--PLERTLELIAERCSLAQALR 206
            :...|..:..:|...||:|:.:..|:..:...:.:..::...|  |.:.....|....:||..|.
pombe   186 VNTMYDHIVVKLVTGLKYEQAKRNYVENECIHILKLTEKYSSQNVPFDVYAAQIPHHSNLASVLA 250

  Fly   207 SIFHDLCT--TGLLSTSLNHNLTLCFCLPAKAHQLHKKGSMVDPETIDRCLRA------------ 257
            :.:..|..  |..|..:.:.||:|.:.:....:.|......|.|.||   |.:
pombe   251 TTYEALINMHTAYLEINQSINLSLLWPMSVSTNTLENYELQVRPSTI---LASQTIFSEEHPSSI 312

  Fly   258 ---LKPYHGMLLLVDFAELLDCVPPTGARMLWQLVDVYDPLISLQSMSSNADLSIEHVYKLVSHL 319
               :.||..:|||.|...::..||.....:|...:.:..|.::...:::...:|:...:.|..||
pombe   313 EPFVAPYWTLLLLKDTDTIMKRVPLLQNSLLSSFIAIVKPNLTFTDIANRLGISVSECFILAKHL 377

  Fly   320 VYWAKATIIYPLCETNVYVIAPDA---PLHTKSHLVEKFSARFAGMSLFEVISDFSLPTSIGHLT 381
            ::|.||..|.||...|.||.:|.|   .|..:|.|.:|.......:|.|..|..|. |.....:
pombe   378 IHWRKAIAIPPLLIRNTYVTSPTANLFNLEEESKLFKKEFPSLPSLSTFLAILSFK-PRPFASI- 440

  Fly   382 TPLQQPARQGILAQMVIWMLQHHLLMQLHTYVQFM-PSEDEFGDSASCSNHLRDAISDEEGDQEP 445
              :.....:.:..:|:.|:.:.:.:.:.:.|:..: |.|.:           :.||:..|.|:..
pombe   441 --IPSKDHELVYLEMLAWLCRRNWVYEQNIYMYILVPEEIK-----------KKAIALIESDESS 492

  Fly   446 DAD-ELHGSMLSMSSHPLPVPAVLVGGHRREASEDHSSLASDNIAVQPSSSHKSNFSITASMSTD 509
            ..| :|                      |::..:|:   ..::|.:.|.|         ||:.
pombe   493 KNDMQL----------------------RKQLEQDN---GKESIIIDPHS---------ASLL-- 521

  Fly   510 NCDSLDSMEDEQKLKELLQVFSDADRAAIRRIPASANVDDLSLLVKLYQMGYFKSEHHLEEIMYF 574
                      |||..:::         |..|.|..|.:  .:.:||     |......|:.|...
pombe   522 ----------EQKWIQII---------AYERGPEMAPL--FTSIVK-----YLNGRFALQTIWVA 560

  Fly   575 ENLRRSQLLQLLDKFRDVLI 594
            |.|.|..:..:|:::.|.::
pombe   561 EGLPRKLMRNILNEYNDYIL 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nprl3	NP_001261818.1	NPR3	76..413	CDD:305178	81/400 (20%)
SPBC543.04	NP_001342971.1	NPR3	76..479	CDD:308971	85/413 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	66	1.000	Domainoid score	I2811
eggNOG	1	0.900	-	-		E1_KOG3830
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1859
OMA	1	1.010	-	-		QHG53225
OrthoFinder	1	1.000	-	-		FOG0006449
OrthoInspector	1	1.000	-	-		oto100806
orthoMCL	1	0.900	-	-		OOG6_104131
Panther	1	1.100	-	-	LDO	PTHR13153
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R838
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.860