DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17359 and ZBTB45

DIOPT Version :9

Sequence 1:NP_648679.1 Gene:CG17359 / 39549 FlyBaseID:FBgn0036396 Length:339 Species:Drosophila melanogaster
Sequence 2:NP_001303907.1 Gene:ZBTB45 / 84878 HGNCID:23715 Length:511 Species:Homo sapiens


Alignment Length:237 Identity:70/237 - (29%)
Similarity:104/237 - (43%) Gaps:29/237 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   106 DNIEPQMPVSVM--EAGKTPE---TSEPLLVELVQVKYMPP---EPKP--------ISSPLPDNN 154
            :::.|...||..  |.|..||   |..|:..:.:.....||   .|.|        :.:|.|...
Human   280 EDVFPDSYVSTWHDEDGAVPEGCPTETPVQPDCILSGSRPPGVKTPGPPVALFPFHLGAPGPPAP 344

  Fly   155 EHKLAQSYSPAKTPHNKSKRRARSYSDNDSWSPDSEL-EHEDDDKIWNASKRGKPKRVPG----P 214
            ........:||..|......:..:       :|.::| |..........:..|.|.|.||    .
Human   345 PPSAPSGPAPAPPPAFYPTLQPEA-------APSTQLGEVPAPSAAPTTAPSGTPARTPGAEPPT 402

  Fly   215 YRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKR 279
            |.|..|.::|:.::|...||.||:||:|::|::|.|||:.:..|..|...|||.|.|.|..|.||
Human   403 YECSHCRKTFSSRKNYTKHMFIHSGEKPHQCAVCWRSFSLRDYLLKHMVTHTGVRAFQCAVCAKR 467

  Fly   280 FRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAH 321
            |.|...|.||.|||..|:. .|..|.:.|.....|::|::||
Human   468 FTQKSSLNVHMRTHRPERA-PCPACGKVFSHRALLERHLAAH 508

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17359NP_648679.1 zf-AD 6..88 CDD:285071
zf-C2H2 215..237 CDD:278523 7/21 (33%)
C2H2 Zn finger 217..237 CDD:275368 6/19 (32%)
zf-H2C2_2 229..254 CDD:290200 13/24 (54%)
C2H2 Zn finger 245..265 CDD:275368 7/19 (37%)
zf-H2C2_2 257..282 CDD:290200 12/24 (50%)
C2H2 Zn finger 273..293 CDD:275368 10/19 (53%)
zf-H2C2_2 286..310 CDD:290200 10/23 (43%)
C2H2 Zn finger 301..321 CDD:275368 5/19 (26%)
ZBTB45NP_001303907.1 BTB 23..122 CDD:279045
BTB 34..124 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 159..241
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 294..403 23/115 (20%)
zf-C2H2 403..425 CDD:278523 7/21 (33%)
COG5048 <405..>472 CDD:227381 29/66 (44%)
C2H2 Zn finger 405..425 CDD:275368 6/19 (32%)
zf-H2C2_2 417..441 CDD:290200 12/23 (52%)
C2H2 Zn finger 433..453 CDD:275368 7/19 (37%)
zf-H2C2_2 445..470 CDD:290200 12/24 (50%)
zf-C2H2 459..481 CDD:278523 11/21 (52%)
C2H2 Zn finger 461..481 CDD:275368 10/19 (53%)
zf-H2C2_2 473..497 CDD:290200 10/24 (42%)
C2H2 Zn finger 488..508 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S4407
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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