DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17359 and zgc:171551

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001107110.1	Gene:	zgc:171551 / 798325	ZFINID:	ZDB-GENE-080220-8	Length:	443	Species:	Danio rerio

Alignment Length:	389	Identity:	99/389 - (25%)
Similarity:	148/389 - (38%)	Gaps:	105/389 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DESDCLLDIYTEPYASSNRVQEQEPV----------------------------LATMLRECSGC 48
            |.....|.:..|.....|.::|:||:                            ::||.::   .
Zfish    23 DPEQTELMVLKEETEELNGIEEKEPMVLKEETQEFNEMEEKDQFEKNQDLMTAEMSTMTKK---T 84

  Fly    49 SVHKED----GMPQFICVECAEAVRNAYRLR--------------RQCRKSHQYFEQLRLM--MK 93
            |..|.|    .:..|.|.:|.::....|:||              .||.|  ::.|:.:|.  |.
Zfish    85 SPRKRDQEIKPVGNFTCSQCGKSFTQKYKLRVHIRVHTGEKPYSCEQCGK--RFIEKSKLASHMS 147

  Fly    94 ELDDI--EYCLNIGDNIEPQMPVSV---MEAGKTPETSEPLLVELVQVKYMPPEPKPISSPLPD- 152
            ...|:  ..|...|...:.:..:::   ...|:.|.:.:...:...|..|:.......|:..|.
Zfish   148 THTDVRPHSCPECGKGFKQKQNLAIHMRTHTGEKPFSCDQCDMSFSQAHYLKAHMNVHSNEKPYA 212

  Fly   153 --------------NNEHKLAQSYSPAKTP-------HNKSKRRARSYSDNDSWSPDSELEHEDD 196
                          .|..||.....|...|       |   |:|..::.
Zfish   213 CQQCGKRFRQIKILRNHIKLHTGEKPCACPQCGMRFIH---KQRIETHM---------------- 258

  Fly   197 DKIWNASKRGKPKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSH 261
             |:.|     |......|:.|:.|.:.|.||..|:||||:||||:||.||.|.:||.||.||:.|
Zfish   259 -KVHN-----KAIEAIKPFLCQQCGKGFVQKGTLKIHMRVHTGEKPYTCSQCGKSFTQKSNLKYH 317

  Fly   262 TRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGK 325
            ...||||:||.|..|...|.|...|::|.|.|.||:|:.||:|.:||.|...|..||..|...|
Zfish   318 MVTHTGEKPFPCQQCGNSFSQKKCLEIHLRLHNGEKPYTCSQCGKSFTQKGNLNSHMRTHAEKK 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	22/121 (18%)
		zf-C2H2	215..237	CDD:278523	10/21 (48%)
		C2H2 Zn finger	217..237	CDD:275368	10/19 (53%)
		zf-H2C2_2	229..254	CDD:290200	16/24 (67%)
		C2H2 Zn finger	245..265	CDD:275368	10/19 (53%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..321	CDD:275368	9/19 (47%)
zgc:171551	NP_001107110.1	COG5048	66..>439	CDD:227381	92/346 (27%)
		zf-C2H2	99..121	CDD:278523	6/21 (29%)
		C2H2 Zn finger	101..121	CDD:275368	5/19 (26%)
		zf-H2C2_2	114..136	CDD:290200	5/23 (22%)
		C2H2 Zn finger	129..149	CDD:275368	6/21 (29%)
		zf-C2H2	155..177	CDD:278523	2/21 (10%)
		C2H2 Zn finger	157..177	CDD:275368	2/19 (11%)
		zf-H2C2_2	169..194	CDD:290200	2/24 (8%)
		C2H2 Zn finger	185..205	CDD:275368	2/19 (11%)
		zf-H2C2_2	197..222	CDD:290200	3/24 (13%)
		C2H2 Zn finger	213..233	CDD:275368	2/19 (11%)
		C2H2 Zn finger	241..261	CDD:275368	5/39 (13%)
		C2H2 Zn finger	273..293	CDD:275368	10/19 (53%)
		zf-H2C2_2	286..310	CDD:290200	16/23 (70%)
		C2H2 Zn finger	301..321	CDD:275368	10/19 (53%)
		zf-H2C2_2	313..338	CDD:290200	12/24 (50%)
		C2H2 Zn finger	329..349	CDD:275368	7/19 (37%)
		zf-H2C2_2	342..366	CDD:290200	12/23 (52%)
		zf-C2H2	355..377	CDD:278523	9/21 (43%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		C2H2 Zn finger	385..405	CDD:275368
		zf-H2C2_2	398..422	CDD:290200
		C2H2 Zn finger	413..433	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588359
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930