DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and znf576.2

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_017206844.1	Gene:	znf576.2 / 563587	ZFINID:	ZDB-GENE-030131-1738	Length:	2676	Species:	Danio rerio

Alignment Length:	332	Identity:	84/332 - (25%)
Similarity:	125/332 - (37%)	Gaps:	81/332 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLREC----SGCSVHKEDGMP--QFICVECA 65
            |.|| |.:....:..|:..::.|:  |.:|......:||    |..:.|:....|  ||:|.||.
Zfish  2379 CYVC-DRTFPSSEELTQHQSTHNK--EDKPFKCVHCQECFRTFSELTTHRRQVCPERQFVCKECN 2440

  Fly    66 EAVRNAYRLRRQCRKSHQYFEQLRLMM----KELDDIE------YCLNIGDNIEPQMPV------ 114
            |..|:...||     ||      |||.    ::.:|:|      .|...|...|.:..:
Zfish  2441 ETFRSPGLLR-----SH------RLMQHPVPQDEEDVEDPSKTYRCGKCGRGFEEEAELLQHQEN 2494

  Fly   115 -----------SVMEAGKTPETSEPLLVELVQVKY--MPPEPKPISSPLPDNNEHKLAQSYSPAK 166
                       :|...|:.|             ||  ..|..|.:.....|.:..:...|...:.
Zfish  2495 HAGDRHCNGGAAVKRRGRPP-------------KYEAAAPSEKKVKKKKKDEDAEETNHSEDASA 2546

  Fly   167 TPHNKSKRRARSYSDNDSWSPDSELEH-EDDDKIWNASKRGKPKRVPGPYR---CKLCTQSFTQK 227
            |......||.|......  .|::|.|. |:|||          |.||.|.|   |..|..:|...
Zfish  2547 TSAKTGGRRGRPAKSTQ--EPEAEDEKAENDDK----------KSVPEPERQIPCTECDLTFPTL 2599

  Fly   228 QNLEIHMR-IHTGERPYKCSLCPRSFAQKGNLQSH-TRCHTGERPFGCPNCPKRFRQVGQLQVHT 290
            ..|.:|.: .||.::|:.|..|..||.:...||:| .|.|:..| ..||.|.|.|.:...|:.|.
Zfish  2600 TLLRMHKKEKHTQKKPHPCKECEESFNRPAQLQAHMARAHSVGR-HTCPTCGKSFGRESNLKAHQ 2663

  Fly   291 RTHTGEQ 297
            ::|..|:
Zfish  2664 QSHEKEE 2670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	24/86 (28%)
		zf-C2H2	215..237	CDD:278523	6/25 (24%)
		C2H2 Zn finger	217..237	CDD:275368	5/20 (25%)
		zf-H2C2_2	229..254	CDD:290200	9/25 (36%)
		C2H2 Zn finger	245..265	CDD:275368	8/20 (40%)
		zf-H2C2_2	257..282	CDD:290200	11/25 (44%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	4/12 (33%)
		C2H2 Zn finger	301..321	CDD:275368
znf576.2	XP_017206844.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000