DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17359 and znf973

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_021330710.1	Gene:	znf973 / 557295	ZFINID:	ZDB-GENE-080218-9	Length:	354	Species:	Danio rerio

Alignment Length:	299	Identity:	85/299 - (28%)
Similarity:	126/299 - (42%)	Gaps:	68/299 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 FICVECAEAVRNAYRLR--------------RQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIE 109
            |.|.:|.:.:.:..:|:              .||.||......|.|.|:        ::.|:.
Zfish    66 FTCTQCGKILASKSKLKIHMSIHTGEKPFTCTQCGKSFSLSSSLNLHMR--------IHTGEK-- 120

  Fly   110 PQMPVSVMEAGKTPETSEPLLVELVQVKYM--PPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKS 172
               |.:..:.||:.....||      .|:|  ....||.:. ........|:.|.:.....|...
Zfish   121 ---PYTCTQCGKSFSHLSPL------NKHMRIHTGEKPFTC-TQCGKSFSLSTSLNLHMRIHTGE 175

  Fly   173 K-----RRARSYSDNDSWSPDSELEHEDDDKIWNASKR-----GKPKRVPGPYRCKLCTQSFTQK 227
            |     |..:|::.:.                 |.||.     ||.     |:.|..|.:||...
Zfish   176 KPFTCTRCGKSFNCSS-----------------NLSKHMMIHTGKK-----PFTCTQCEKSFRIS 218

  Fly   228 QNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRT 292
            .:|.:||||||||:|:.|:.|..||:|..:|..|.|.||||:||.|..|.|.|.:...|.:|.|.
Zfish   219 SSLNLHMRIHTGEKPFTCTQCGNSFSQSSSLNKHMRIHTGEKPFTCTQCVKSFSRSEHLNLHMRI 283

  Fly   293 HTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGKRRTSSQ 331
            ||||:||.|::|::||...:.|.:||..||..|....:|
Zfish   284 HTGEKPFTCTECEKSFTCSSHLNRHMRKHTGEKPYACTQ 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	8/42 (19%)
		zf-C2H2	215..237	CDD:278523	8/21 (38%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		zf-H2C2_2	229..254	CDD:290200	14/24 (58%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	13/23 (57%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
znf973	XP_021330710.1	C2H2 Zn finger	68..88	CDD:275368	3/19 (16%)
		C2H2 Zn finger	96..116	CDD:275368	7/27 (26%)
		COG5048	120..>337	CDD:227381	73/237 (31%)
		C2H2 Zn finger	124..144	CDD:275368	6/25 (24%)
		C2H2 Zn finger	152..172	CDD:275368	2/20 (10%)
		C2H2 Zn finger	180..200	CDD:275368	5/36 (14%)
		C2H2 Zn finger	208..228	CDD:275368	8/19 (42%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
		C2H2 Zn finger	320..340	CDD:275368	1/3 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000