DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and si:dkey-262g12.9

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_021331485.1	Gene:	si:dkey-262g12.9 / 555910	ZFINID:	ZDB-GENE-161017-28	Length:	380	Species:	Danio rerio

Alignment Length:	239	Identity:	81/239 - (33%)
Similarity:	126/239 - (52%)	Gaps:	29/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 LRLMMKELDD--IEYCLNIGDNIEPQMPVSVM--EAGKTPETSEPLLVELVQVKYMPPEPKPISS 148
            :..:.:|.:|  ||..:...::::.|..:.||  |:.:..||.|....|    |:.....:.||:
Zfish     1 MAFIKEECEDLKIEEIIIKQEDLQEQTDLMVMKEESEELNETEEKDQFE----KHQELMTEEISA 61

  Fly   149 PLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSD-NDSWSPDSELEHEDDDKIWNASKRGKPKRVP 212
                  |.|.|       :||   ||..::.|| |.:.|.......:.::.:.:.|.|.:.|
Zfish    62 ------ETKKA-------SPH---KRAQKTKSDGNFTCSQGGMSFTQKNNLVDHMSARSEEK--- 107

  Fly   213 GPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCP 277
             ||.|..|.:.|.:|..|.:|||:||||:|:.|.||.:||..:.|::.|.|.||||||:.|..|.
Zfish   108 -PYPCPECGKGFRKKHILAVHMRVHTGEKPFSCDLCGKSFNLQKNMKIHRRIHTGERPYACQQCG 171

  Fly   278 KRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAH 321
            |||||:..|:.|.:.||||:|:.|::|..||.|...|:.||:.|
Zfish   172 KRFRQIQILKNHIKLHTGERPYACAQCGMSFIQKQKLEAHMAVH 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	81/239 (34%)
		zf-C2H2	215..237	CDD:278523	9/21 (43%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		zf-H2C2_2	229..254	CDD:290200	14/24 (58%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	14/24 (58%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		zf-H2C2_2	286..310	CDD:290200	11/23 (48%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
si:dkey-262g12.9	XP_021331485.1	COG5048	<75..263	CDD:227381	59/145 (41%)
		C2H2 Zn finger	83..103	CDD:275368	2/19 (11%)
		C2H2 Zn finger	111..131	CDD:275368	8/19 (42%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		COG5048	216..>328	CDD:227381	81/239 (34%)
		C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588301
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930