DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and CG11902

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_651389.3	Gene:	CG11902 / 43070	FlyBaseID:	FBgn0028647	Length:	1426	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	98/341 - (28%)
Similarity:	137/341 - (40%)	Gaps:	91/341 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SQMCRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGC----------SVHK----ED 54
            |..|.:|  :..||...  |.|.....:...|.:    ...|..|          |.||    |:
  Fly  1112 SYTCNMC--QLRCLRKF--ELYQHQQAMHRMEKI----SDGCDSCLFKSVCPEIISHHKRTQCEN 1168

  Fly    55 GMPQFICVECAEAVRNAYRLRRQCR-KSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVME 118
            ...||.|..|      .|:...:.. ..|...:.::...:|||:.:..  .||  ||:....|.:
  Fly  1169 REKQFKCTRC------GYKFMWESNLLLHMDLQHVKTEDQELDESKEA--SGD--EPKTEGQVFQ 1223

  Fly   119 AG---KTPETSEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYS 180
            .|   :.....:.|...|  .|:..|:.||                 |.||||
  Fly  1224 CGLCTRKYNRKDRLTAHL--KKFHGPDCKP-----------------STAKTP------------ 1257

  Fly   181 DNDSWSPDSELEHEDDDKIWNASKRGKPKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKC 245
             |...||.                  :|||    :.|..|.::.:...||.||||.||||:|:||
  Fly  1258 -NRPISPK------------------EPKR----FLCAFCGKAVSSSSNLIIHMRRHTGEKPFKC 1299

  Fly   246 SLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQ 310
            ..|..:|.:..:||.|.|.||||||..|..|.|.|.:..:||.|.|.|:||:|:||:.|::||.|
  Fly  1300 EYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQ 1364

  Fly   311 LNGLQKHMSAHTRGKR 326
            .|.|..|:..|| |:|
  Fly  1365 SNDLTLHIRRHT-GER 1379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	19/96 (20%)
		zf-C2H2	215..237	CDD:278523	8/21 (38%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		zf-H2C2_2	229..254	CDD:290200	15/24 (63%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	14/24 (58%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	13/23 (57%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
CG11902	NP_651389.3	zf-AD	6..83	CDD:285071
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	384..405	CDD:275368
		C2H2 Zn finger	417..437	CDD:275368
		C2H2 Zn finger	447..463	CDD:275368
		C2H2 Zn finger	578..599	CDD:275368
		C2H2 Zn finger	610..629	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	706..726	CDD:275368
		C2H2 Zn finger	762..782	CDD:275368
		C2H2 Zn finger	866..887	CDD:275368
		C2H2 Zn finger	896..918	CDD:275368
		C2H2 Zn finger	926..947	CDD:275368
		C2H2 Zn finger	967..987	CDD:275368
		C2H2 Zn finger	996..1016	CDD:275368
		C2H2 Zn finger	1044..1063	CDD:275368
		C2H2 Zn finger	1224..1244	CDD:275368	3/21 (14%)
		C2H2 Zn finger	1271..1291	CDD:275368	8/19 (42%)
		zf-H2C2_2	1283..1306	CDD:290200	14/22 (64%)
		COG5048	1295..>1367	CDD:227381	33/71 (46%)
		C2H2 Zn finger	1299..1319	CDD:275368	7/19 (37%)
		zf-H2C2_2	1311..1336	CDD:290200	14/24 (58%)
		C2H2 Zn finger	1327..1347	CDD:275368	8/19 (42%)
		zf-H2C2_2	1340..1364	CDD:290200	13/23 (57%)
		C2H2 Zn finger	1355..1375	CDD:275368	8/19 (42%)
		zf-H2C2_2	1367..1392	CDD:290200	6/14 (43%)
		C2H2 Zn finger	1383..1401	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010