DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and CG4854

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	98/341 - (28%)
Similarity:	149/341 - (43%)	Gaps:	58/341 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRVC----RDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAEA 67
            ||:|    :|||                :...||.....::.|:|..:.:....|..||..||..
  Fly    12 CRICLVQPKDES----------------LMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALL 60

  Fly    68 VRNAYRLRRQCRKSHQYFEQLRLM-------------MKELDDIEYCLNIGDNIEPQMPVSVMEA 119
            :|.|.:||..|:::.:..::.:|.             .|:.:..:...|.....:.::....:::
  Fly    61 LRAALKLRSLCQQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDS 125

  Fly   120 -GKTPETSEPLLV---ELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAK-TPHNKSKRRARSY 179
             ..|.|:||.:..   |||.:     || .||:|      .:...|.||.. |..::...:|.|:
  Fly   126 YDVTLESSEDVACSADELVSI-----EP-AISAP------EESVYSLSPKPVTFEDEDSGQAASF 178

  Fly   180 SDNDSWSPDSELEHEDDDKIWNASKRGKPKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYK 244
            :.|...:..||..     |:.|..|....|:   |:.|::|.:.|.|...|..||..|||.||||
  Fly   179 TCNICNNVYSERV-----KLTNHMKVHSAKK---PHECEICHKRFRQTPQLARHMNTHTGNRPYK 235

  Fly   245 CSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFK 309
            |..|...||.......|.|.||.|||:.|..|.:.|.....|:||.:|||||:||.|..||:||.
  Fly   236 CDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFS 300

  Fly   310 QLNGLQKHMSAHTRGK 325
            ||:....|..:|.|.|
  Fly   301 QLHHKNSHEKSHKRTK 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	20/84 (24%)
		zf-C2H2	215..237	CDD:278523	7/21 (33%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		zf-H2C2_2	229..254	CDD:290200	13/24 (54%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	15/23 (65%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	13/60 (22%)
		C2H2 Zn finger	180..200	CDD:275368	6/24 (25%)
		zf-H2C2_2	193..217	CDD:290200	7/26 (27%)
		COG5048	201..>258	CDD:227381	23/59 (39%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	12/22 (55%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		zf-H2C2_2	251..273	CDD:290200	10/21 (48%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	15/23 (65%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910