DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and M1BP

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	95/427 - (22%)
Similarity:	144/427 - (33%)	Gaps:	131/427 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ISQMCRVCRDESDCLLDIYTEPYASSNR----VQEQEPVLATMLRECSGCSVHKEDGMPQFICVE 63
            :...||||            ..|||:.|    .:.....:...:...:|..:.....:|..||..
  Fly     9 LKSTCRVC------------AKYASNKRSPKLFERSNTKMIDNIEALTGLRLENYGCLPDQICEC 61

  Fly    64 CAEAVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVS-----------VM 117
            |:..:.:|.:||.:|..:.:   :|.|.:.|              |.:..:|           ::
  Fly    62 CSMELASAVKLRERCIAAQR---ELLLGLTE--------------EQRQGISAFYRAAVMGEDIV 109

  Fly   118 EAGKTPETSEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQ---------------SYSPAKT 167
            :..|||:..|........|...|.|....:....||..:::|:               .|.....
  Fly   110 QTVKTPDDDEVYATYQEIVLEEPKEEIDDTKVEYDNTYYEVAEGHAGEDDAASLIEEADYDSIMA 174

  Fly   168 PHNKSKRRARSYSD--------NDSWSPDS-------------ELEHED---------------- 195
            ...:.::......|        ||::..||             |.|||:
  Fly   175 EDEEQQQTLELDEDTELIVGDVNDAYVYDSDDEVAVLDNVLDDEYEHENIVVKKCSLPPKPKVRS 239

  Fly   196 DDKIWNASKRG------------------------KPKRVPGPYRCKLCTQSFTQKQNLEIHMRI 236
            ||    |.:||                        :..|....:.|:||...|.....|:.|||.
  Fly   240 DD----ARRRGTGGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRK 300

  Fly   237 HTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKC 301
            ||||||:.|..|.|.|........|.|.||.|||:.|..|.|.|.....|:.|...|:||:.::|
  Fly   301 HTGERPFACKYCGRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRC 365

  Fly   302 SKCQQSFKQLNGLQKHMSAHTRG---KRRTSSQETKR 335
            ..|.:||.    |..|:|.|.|.   ||.....|.|:
  Fly   366 ELCDKSFM----LPTHLSTHFRSGVHKRHLEKAEMKQ 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	17/85 (20%)
		zf-C2H2	215..237	CDD:278523	8/21 (38%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		zf-H2C2_2	229..254	CDD:290200	14/24 (58%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	11/24 (46%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	9/23 (39%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	17/85 (20%)
		C2H2 Zn finger	253..273	CDD:275368	0/19 (0%)
		COG5048	276..>331	CDD:227381	21/54 (39%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		zf-H2C2_2	293..317	CDD:290200	13/23 (57%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		zf-H2C2_2	324..346	CDD:290200	11/21 (52%)
		C2H2 Zn finger	337..357	CDD:275368	6/19 (32%)
		zf-H2C2_2	350..372	CDD:290200	7/21 (33%)
		C2H2 Zn finger	365..383	CDD:275368	8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000