DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17359 and ouib

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	331	Identity:	93/331 - (28%)
Similarity:	139/331 - (41%)	Gaps:	68/331 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MCRVCRDESDC-----LLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECA 65
            :||||..:..|     |.|:....|...             |...||..:...|.:|.|:|:.|.
  Fly     5 VCRVCGRQKICEKSLNLFDLVNRKYLKH-------------LHMISGLRLVDLDDVPGFMCLCCQ 56

  Fly    66 EAVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQM-PVSVMEAGKTPETSEPL 129
            ..:|:|...|:.|.|:     |.:.:..|.|......:..||.|.:. ..:..:.||..|..  |
  Fly    57 AELRSALAFRKLCIKT-----QTKWLTIEDDSSSGDEDTNDNSELESEKCAFSDFGKKKEGE--L 114

  Fly   130 LVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDNDSWSPDSEL--- 191
            :.|..||..   |.:|:.                  ||.:..:|.:.|....::...|..::
  Fly   115 VEETFQVLI---EEEPMD------------------KTLNRDAKAQLREDGIDEKCVPSQKIIKV 158

  Fly   192 EHEDDDKIWNASKRGKPKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKG 256
            ..:.||:|               |.|:||....|.|...:.|||.|.||||:.|..|...|...|
  Fly   159 STKLDDQI---------------YICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAG 208

  Fly   257 NLQSHTRCHTGERPFGCPNCPKRF-RQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSA 320
            .|::|.|.||||:||.|..|.||: ..:|:| :|.||||.::|:.|.:|.:.|.....|:.||..
  Fly   209 ELRAHHRVHTGEQPFACRFCEKRYVSYMGRL-IHERTHTNDRPYVCEECGKKFTTAYVLKNHMVI 272

  Fly   321 HTRGKR 326
            || |:|
  Fly   273 HT-GER 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	21/86 (24%)
		zf-C2H2	215..237	CDD:278523	9/21 (43%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		zf-H2C2_2	229..254	CDD:290200	11/24 (46%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	13/25 (52%)
		C2H2 Zn finger	273..293	CDD:275368	8/20 (40%)
		zf-H2C2_2	286..310	CDD:290200	10/23 (43%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	22/90 (24%)
		COG5048	<158..300	CDD:227381	52/137 (38%)
		C2H2 Zn finger	169..189	CDD:275368	8/19 (42%)
		C2H2 Zn finger	197..217	CDD:275368	7/19 (37%)
		zf-H2C2_2	209..234	CDD:290200	13/24 (54%)
		C2H2 Zn finger	225..245	CDD:275368	8/20 (40%)
		zf-H2C2_2	241..262	CDD:290200	9/20 (45%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		zf-H2C2_2	266..288	CDD:290200	7/13 (54%)
		C2H2 Zn finger	281..299	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000