DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and Zif

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	89/393 - (22%)
Similarity:	146/393 - (37%)	Gaps:	106/393 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QMCRVCRDESDCL--LD-IYTEPYASSNRVQEQEPVLATMLRECSGCS---VHKEDGMPQFICVE 63
            |.||||..:|:.|  || |..|...|.|.          ||.:..|.|   ::..:.:|..||..
  Fly     8 QTCRVCLAQSERLQRLDEIREEGEESPNE----------MLIQLLGVSYSNLNDREHIPDGICKS 62

  Fly    64 CAEAVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEP 128
            |...:..||:.|.            :.:.|:::..|||..:|...|..:.:...|.|...:..|.
  Fly    63 CKVELNMAYQFRE------------KALRKQMEIEEYCRELGLLDESDVMMIKEEDGSQQQCDEE 115

  Fly   129 LLV-------------ELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSK-----RR 175
            :.:             |....:|:..:.......:.|..|: |..:|:   ...|..:     ..
  Fly   116 MYILEETTTGEEEHQEEKGHEEYLEVDTSDQQECIGDTIEY-LEDNYT---IEMNSDQTEIVLES 176

  Fly   176 ARSYSDNDSWSPDSELEHEDDDKIWNASKRGKPKR-------------------VPG-------- 213
            .:.|.:    :|..:|..::..|....::||:.:|                   |.|
  Fly   177 EKQYEE----TPSQQLALQEAAKASLKARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGR 237

  Fly   214 ------------PYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHT 266
                        .|.|:||...|..::.|..||..|||.:|||||.|.|.|..:..|:||...|.
  Fly   238 MMEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHENVHR 302

  Fly   267 GERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGKRRTSSQ 331
            |.:|:.|..|.|.|.....|..|...|:..:.::|..|.:.|:.|:.:::|             :
  Fly   303 GIKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQH-------------E 354

  Fly   332 ETK 334
            |||
  Fly   355 ETK 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	23/87 (26%)
		zf-C2H2	215..237	CDD:278523	8/21 (38%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		zf-H2C2_2	229..254	CDD:290200	14/24 (58%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	6/23 (26%)
		C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071	24/99 (24%)
		C2H2 Zn finger	225..245	CDD:275368	2/19 (11%)
		COG5048	<250..369	CDD:227381	40/121 (33%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	266..288	CDD:290200	13/21 (62%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		zf-H2C2_2	294..318	CDD:290200	10/23 (43%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		C2H2 Zn finger	337..353	CDD:275368	4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930