DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and CG17328

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_609786.2	Gene:	CG17328 / 34962	FlyBaseID:	FBgn0028895	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	106/348 - (30%)
Similarity:	154/348 - (44%)	Gaps:	81/348 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DISQMCRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAE 66
            :|.::||||.:|...:..||:..:|....|         ||.:|:...|.|.||:|..||..|..
  Fly     4 NIHKICRVCLEELHPVTSIYSTDFAMMPSV---------MLMQCAKIRVFKTDGLPSVICNNCIY 59

  Fly    67 AVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLLV 131
            .:..|:..:::|..|     .|||.       :|             :.::|:.:....:....|
  Fly    60 RLGVAFHFKQECENS-----DLRLR-------QY-------------LGILESWRQDAATNTDFV 99

  Fly   132 ELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDNDSWSPDSELEHEDD 196
            |           ||: .|..|::|.:...    ||.    ||||:|       :......||:
  Fly   100 E-----------KPL-LPQRDSDEEEPVD----AKV----SKRRSR-------YQRKPPEEHK-- 135

  Fly   197 DKIWNASKRGKPKRVPG-PYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQS 260
                   ||| ||.||. |:.|..|.:||.....|..|:|.||||:||:||.|.:.||||.||:.
  Fly   136 -------KRG-PKPVPKMPHTCYECHKSFKCIAQLTQHIRTHTGEKPYQCSFCIQRFAQKYNLKV 192

  Fly   261 HTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTR-- 323
            |.|.|||::||.|..|.|:|..:|..|.|.:.|.|.:...||.||:.|.....|.|||..||.
  Fly   193 HERTHTGDKPFQCEICSKQFSALGNFQAHQKIHLGVRDQVCSLCQKGFYTAGDLSKHMITHTGIK 257

  Fly   324 -------GKRRTSSQETKRNKFK 339
                   ||..:..::.:.:|.|
  Fly   258 NHHCDVCGKAFSRRRDMRTHKLK 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	23/81 (28%)
		zf-C2H2	215..237	CDD:278523	7/21 (33%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		zf-H2C2_2	229..254	CDD:290200	13/24 (54%)
		C2H2 Zn finger	245..265	CDD:275368	11/19 (58%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	9/23 (39%)
		C2H2 Zn finger	301..321	CDD:275368	9/19 (47%)
CG17328	NP_609786.2	zf-AD	8..80	CDD:214871	26/92 (28%)
		COG5048	146..>211	CDD:227381	32/64 (50%)
		C2H2 Zn finger	149..169	CDD:275368	7/19 (37%)
		C2H2 Zn finger	177..197	CDD:275368	11/19 (58%)
		zf-H2C2_2	189..213	CDD:404364	12/23 (52%)
		C2H2 Zn finger	205..225	CDD:275368	7/19 (37%)
		C2H2 Zn finger	233..253	CDD:275368	9/19 (47%)
		zf-H2C2_2	245..270	CDD:404364	8/24 (33%)
		C2H2 Zn finger	261..282	CDD:275368	4/20 (20%)
		C2H2 Zn finger	318..338	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910