DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17359 and ZNF774

DIOPT Version :9

Sequence 1:NP_648679.1 Gene:CG17359 / 39549 FlyBaseID:FBgn0036396 Length:339 Species:Drosophila melanogaster
Sequence 2:NP_001004309.2 Gene:ZNF774 / 342132 HGNCID:33108 Length:483 Species:Homo sapiens


Alignment Length:350 Identity:92/350 - (26%)
Similarity:133/350 - (38%) Gaps:94/350 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 CSGCS------------VHKEDGMPQFICVECAEAVRNAYRL---RR--------QCRKSHQYFE 86
            |:.|.            :....|...:.|:||.:..:.:..|   ||        ||:...:.|.
Human   153 CAECGKSFNQSSYLIRHLRTHTGERPYTCIECGKGFKQSSDLVTHRRTHTGEKPYQCKGCEKKFS 217

  Fly    87 QLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLLVELVQVKYMPPEPKPISSPLP 151
            ....::|     ....:.|:.     |....|.||| ...:|.|:       |.........|..
Human   218 DSSTLIK-----HQRTHTGER-----PYECPECGKT-FGRKPHLI-------MHQRTHTGEKPYA 264

  Fly   152 DNNEHKLAQSYSPAKT--PHNKSKRRARSYSDND---SWSPDSEL-EHE---DDDKIWNASKRGK 207
            ....||   |:|.:..  .|.::....:.|..||   |:|..|:| :|:   ..::.:...:.||
Human   265 CLECHK---SFSRSSNFITHQRTHTGVKPYRCNDCGESFSQSSDLIKHQRTHTGERPFKCPECGK 326

  Fly   208 -------------------PKRVPG----------------------PYRCKLCTQSFTQKQNLE 231
                               |...|.                      |::|:.|.:.|.....|.
Human   327 GFRDSSHFVAHMSTHSGERPFSCPDCHKSFSQSSHLVTHQRTHTGERPFKCENCGKGFADSSALI 391

  Fly   232 IHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGE 296
            .|.|||||||||||..|.:||.|..:..:|.|.|.|:||:.||.|.|.|.|......|.||||||
Human   392 KHQRIHTGERPYKCGECGKSFNQSSHFITHQRIHLGDRPYRCPECGKTFNQRSHFLTHQRTHTGE 456

  Fly   297 QPFKCSKCQQSFKQLNGLQKHMSAH 321
            :||.||||.:||:|...|..|.:.|
Human   457 KPFHCSKCNKSFRQKAHLLCHQNTH 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17359NP_648679.1 zf-AD 6..88 CDD:285071 12/65 (18%)
zf-C2H2 215..237 CDD:278523 6/21 (29%)
C2H2 Zn finger 217..237 CDD:275368 6/19 (32%)
zf-H2C2_2 229..254 CDD:290200 16/24 (67%)
C2H2 Zn finger 245..265 CDD:275368 7/19 (37%)
zf-H2C2_2 257..282 CDD:290200 11/24 (46%)
C2H2 Zn finger 273..293 CDD:275368 8/19 (42%)
zf-H2C2_2 286..310 CDD:290200 15/23 (65%)
C2H2 Zn finger 301..321 CDD:275368 9/19 (47%)
ZNF774NP_001004309.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 81..101
COG5048 152..483 CDD:227381 91/349 (26%)
C2H2 Zn finger 153..173 CDD:275368 2/19 (11%)
zf-H2C2_2 165..190 CDD:290200 4/24 (17%)
C2H2 Zn finger 181..201 CDD:275368 6/19 (32%)
zf-H2C2_2 193..217 CDD:290200 5/23 (22%)
C2H2 Zn finger 209..229 CDD:275368 3/24 (13%)
zf-H2C2_2 222..246 CDD:290200 7/34 (21%)
C2H2 Zn finger 237..257 CDD:275368 7/27 (26%)
zf-H2C2_2 249..274 CDD:290200 6/34 (18%)
C2H2 Zn finger 265..285 CDD:275368 5/22 (23%)
zf-H2C2_2 277..302 CDD:290200 5/24 (21%)
zf-C2H2 291..313 CDD:278523 8/21 (38%)
C2H2 Zn finger 293..313 CDD:275368 7/19 (37%)
zf-H2C2_2 305..328 CDD:290200 4/22 (18%)
C2H2 Zn finger 321..341 CDD:275368 2/19 (11%)
zf-C2H2 347..369 CDD:278523 1/21 (5%)
C2H2 Zn finger 349..369 CDD:275368 1/19 (5%)
zf-H2C2_2 361..385 CDD:290200 3/23 (13%)
C2H2 Zn finger 377..397 CDD:275368 6/19 (32%)
zf-H2C2_2 389..414 CDD:290200 16/24 (67%)
C2H2 Zn finger 405..425 CDD:275368 7/19 (37%)
zf-H2C2_2 417..442 CDD:290200 11/24 (46%)
zf-C2H2 431..453 CDD:278523 8/21 (38%)
C2H2 Zn finger 433..453 CDD:275368 8/19 (42%)
zf-H2C2_2 445..470 CDD:290200 15/24 (63%)
C2H2 Zn finger 461..481 CDD:275368 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.