DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and CG11695

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	78/398 - (19%)
Similarity:	148/398 - (37%)	Gaps:	88/398 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MCRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAEAVRN 70
            :||:|.|:::..:.|:.:..:....|...   ||.::.:.....:...||:.:.:|.:|.:.:.:
  Fly     2 ICRLCLDDAEHSVPIFDQDDSGDQPVPSN---LAELIEKHLQLVLLPNDGVSKSLCTQCWQQLAD 63

  Fly    71 AYRLRRQCRKSHQYFEQLRL-MMKELDDIEYCLNIGDNIEPQMPVSVMEA---------GKTPET 125
            ..:......|.....:||:: ...|.:|.:....|  ..||::.||...|         |.....
  Fly    64 FEQFCAMVMKKQLGLQQLKMEPFSEDEDADTKAQI--LCEPEIDVSPAAADNEECNEIDGDASSN 126

  Fly   126 SEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDNDSWSPDSE 190
            |....:....::.|       ..|.|.....:|.::.:..||...|:|.|.:::........|:|
  Fly   127 SRSSSIRTTSLREM-------RLPSPIRRRMRLPRAVTAPKTQAVKAKARTKTHKAEADEDEDAE 184

  Fly   191 LEHEDDDKIWNA-----------------------------------------------SKRGKP 208
            .|.:.:.:..|:                                               .:|.|.
  Fly   185 GEGDPESRSSNSREMDSYIALHGRLECCICGGDEQFPNFAEMKRHFRNHHQSLGYVVCCQRRYKK 249

  Fly   209 KRV----------PGPYRCKLCTQSFTQKQNLEIHM-RIHTG--ERPYKCSLCPRSFAQKGNLQS 260
            :.:          |..:|||:|::....:.:.::|| |.|..  :..:.|..|.:.|:::..|..
  Fly   250 RALYVDHLHMHNDPNYFRCKICSKQLVSRISYDVHMLRFHPNKDDLSFACDQCSKRFSKQFLLTI 314

  Fly   261 HTRCHTGERPFGCPNCPKRFRQVGQLQVH-TRTH-TGEQPFKCSKCQQSFKQLNGLQKHMSAHTR 323
            |:|.|..||...|.:|.:.||....|::| .||| ....||.|..|...||    .::::..|.|
  Fly   315 HSRVHQQERNEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFK----TKQNLLVHKR 375

  Fly   324 GKRRTSSQ 331
            ...|..||
  Fly   376 TVHREGSQ 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	13/81 (16%)
		zf-C2H2	215..237	CDD:278523	7/22 (32%)
		C2H2 Zn finger	217..237	CDD:275368	6/20 (30%)
		zf-H2C2_2	229..254	CDD:290200	7/27 (26%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	9/24 (38%)
		C2H2 Zn finger	273..293	CDD:275368	7/20 (35%)
		zf-H2C2_2	286..310	CDD:290200	10/25 (40%)
		C2H2 Zn finger	301..321	CDD:275368	4/19 (21%)
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071	13/81 (16%)
		C2H2 Zn finger	268..289	CDD:275368	6/20 (30%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..348	CDD:275368	7/20 (35%)
		C2H2 Zn finger	357..376	CDD:275368	5/22 (23%)
		C2H2 Zn finger	389..409	CDD:275368
		C2H2 Zn finger	420..440	CDD:275368
		C2H2 Zn finger	448..468	CDD:275368
		C2H2 Zn finger	476..494	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100