DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and CG2129

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	80/366 - (21%)
Similarity:	133/366 - (36%)	Gaps:	88/366 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSV-HKEDGMPQFIC---VECAEAV 68
            ||..::.|  .|....|..|..:.|:.:.:.:..||:.....| :||:...|..|   ::.....
  Fly   111 RVVLEKQD--EDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQEECGMELDLDSEG 173

  Fly    69 RNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLLVEL 133
            |::.::...|....:.::..:::.:.:     .....|.:.|.                   |:.
  Fly   174 RHSAKIPHSCPHCTKVYQSRKVLERHI-----MRQHKDTLSPD-------------------VDS 214

  Fly   134 VQVKYMPPEPKPISSPLPDNNEHKLAQSYS---PAKTPHNKSKRRARSYSDNDSWSP-------- 187
            ....|.||:..|:.|         .||.|.   ..|..|.|...|.....|:|:...
  Fly   215 EDADYEPPKDAPVKS---------AAQEYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTC 270

  Fly   188 ---DSEL----------------------------EHE-DDDKIWNASKRGKPKRVPGPYRCKLC 220
               :::|                            .|| ...::.:.|:|..|...||      |
  Fly   271 LECEAQLPRLRLLDEHMVQAHGGAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPG------C 329

  Fly   221 TQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQ 285
            .:.|...:::..|.::||.::.:.|..|..|...|..|:.|.|.|||||||||..|.|||.....
  Fly   330 GKRFFTIRHMRNHGKVHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSG 394

  Fly   286 LQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGKR 326
            |:.|...|:.|:|..||.|..:|.:..||..|...|...|:
  Fly   395 LREHMAMHSTERPHVCSVCGATFSRQKGLYHHKFLHADTKQ 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	16/83 (19%)
		zf-C2H2	215..237	CDD:278523	3/21 (14%)
		C2H2 Zn finger	217..237	CDD:275368	3/19 (16%)
		zf-H2C2_2	229..254	CDD:290200	6/24 (25%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	16/24 (67%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	9/23 (39%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	2/19 (11%)
		zf-C2H2_8	323..411	CDD:292531	33/93 (35%)
		C2H2 Zn finger	327..346	CDD:275368	5/24 (21%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	367..389	CDD:290200	14/21 (67%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-H2C2_2	395..419	CDD:290200	9/23 (39%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	438..458	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100