DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17359 and Zfp418

DIOPT Version :10

Sequence 1:NP_648679.1 Gene:CG17359 / 39549 FlyBaseID:FBgn0036396 Length:339 Species:Drosophila melanogaster
Sequence 2:NP_001178549.1 Gene:Zfp418 / 292548 RGDID:1311663 Length:660 Species:Rattus norvegicus


Alignment Length:365 Identity:99/365 - (27%)
Similarity:148/365 - (40%) Gaps:84/365 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 DESDCL--LDIYTEPYASSN------RVQEQEPVLATMLRECSGCSVH-------KEDGMPQFIC 61
            ||:..|  ||:..|.:...:      ..:.:|...|..|.:.....|.       ::...|..||
  Rat    43 DEAQRLLYLDVMLENFTLISSLVYRYEAEAEEKTCAQSLSQTEAPQVRTPKQGQLRQKPHPSDIC 107

  Fly    62 VECAEAVRNAYRLRRQ-------CRK--SHQYFEQLRLMMKELDD-IEYCL-NIGDNIEPQMPVS 115
            :...:.:.:...|..|       |.|  .|::......:.:::|. ::.|: ::..|     |..
  Rat   108 ITVLKDILHLNDLPGQKPYLTEVCTKPQDHKHHRAKNWLKRDVDSLVKSCIFHVAGN-----PFI 167

  Fly   116 VMEAGKTPETSEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKR-----R 175
            ..:.|:    ..|.:..|:|.|.:|            |.|.:            ||.||     |
  Rat   168 CSKIGE----KFPAIWNLLQPKDIP------------NGEKQ------------NKIKRGKAFHR 204

  Fly   176 ARSYSDNDSWSPDSELEHEDDDKIWNASKRG----------------KPKRVP----GPYRCKLC 220
            .::.|::|.:...|..:|...:.....|.:|                .|.|:.    .||.|.:|
  Rat   205 DKNNSESDEYKKSSSPQHRLHEYPGVCSAKGGFESNSCEQDLNKYSPAPFRMDQTENRPYECHVC 269

  Fly   221 TQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQ 285
            .:.|.||..|.||.|.||||:||||..|.:||.|..||..|.|.|:|||||.|..|.|.|.....
  Rat   270 GKWFGQKATLRIHQRRHTGEKPYKCGECGKSFCQSSNLSEHCRVHSGERPFECLECGKAFGCHSS 334

  Fly   286 LQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGK 325
            |..|.||||||.|::||.|.:.|:|:..|..|...||..|
  Rat   335 LLRHQRTHTGEWPYECSDCGRLFRQIVSLITHQRTHTTEK 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17359NP_648679.1 zf-AD 6..88 CDD:462262 18/99 (18%)
SFP1 <131..317 CDD:227516 71/210 (34%)
C2H2 Zn finger 217..237 CDD:275368 9/19 (47%)
zf-H2C2_2 229..254 CDD:463886 15/24 (63%)
C2H2 Zn finger 245..265 CDD:275368 9/19 (47%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
C2H2 Zn finger 301..321 CDD:275368 7/19 (37%)
Zfp418NP_001178549.1 KRAB 24..64 CDD:460171 6/20 (30%)
C2H2 Zn finger 266..286 CDD:275368 9/19 (47%)
COG5048 290..647 CDD:227381 41/85 (48%)
C2H2 Zn finger 294..314 CDD:275368 9/19 (47%)
C2H2 Zn finger 322..342 CDD:275368 7/19 (37%)
C2H2 Zn finger 350..370 CDD:275368 7/19 (37%)
C2H2 Zn finger 378..398 CDD:275368
C2H2 Zn finger 406..426 CDD:275368
C2H2 Zn finger 434..454 CDD:275368
C2H2 Zn finger 462..482 CDD:275368
C2H2 Zn finger 490..510 CDD:275368
C2H2 Zn finger 518..538 CDD:275368
C2H2 Zn finger 546..566 CDD:275368
C2H2 Zn finger 574..594 CDD:275368
C2H2 Zn finger 602..622 CDD:275368
C2H2 Zn finger 630..650 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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