DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and let-391

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_491744.3	Gene:	let-391 / 182953	WormBaseID:	WBGene00006492	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	194	Identity:	50/194 - (25%)
Similarity:	82/194 - (42%)	Gaps:	41/194 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 DSW----SPDSELEHEDDDKIWN------ASKRGKPKRVPGPYRCKLCTQSFTQKQNLEIHMRIH 237
            :.|    :||::.|||:.::|..      ..|:|..| :|....|::|..:......:..|||.|
Worm    16 EEWAAECTPDAQKEHEELEEIVKIPDSTYRKKKGNQK-LPTVTTCEVCGVALKYPSRIMEHMRTH 79

  Fly   238 TGERPYKCSLCPRSFAQKGNLQSHTRC-HTGERPFGCP-NCPKRFRQVGQLQVHTRTHTG----- 295
            |||:||:|.:|...|.|:..:.:|.|. |.|:.||.|. .|.|||....:...|..:|.|
Worm    80 TGEKPYECDICGMRFTQRTPMINHFRVQHMGDLPFLCNFGCGKRFVNNSRRTAHELSHNGLKRAG 144

  Fly   296 -----EQPFK---CSKCQQSFKQLNGLQKHMSAHT---------------RGKRRTSSQETKRN 336
                 .:|.|   |..........:.|..::|..|               ..:.::|:|.||::
Worm   145 PARPYLKPVKKIVCPSMDMDILSNSALANYISPPTIDSIFQSDPSTSSSSPSQFQSSNQTTKQS 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071
		zf-C2H2	215..237	CDD:278523	5/21 (24%)
		C2H2 Zn finger	217..237	CDD:275368	5/19 (26%)
		zf-H2C2_2	229..254	CDD:290200	12/24 (50%)
		C2H2 Zn finger	245..265	CDD:275368	6/20 (30%)
		zf-H2C2_2	257..282	CDD:290200	11/26 (42%)
		C2H2 Zn finger	273..293	CDD:275368	6/20 (30%)
		zf-H2C2_2	286..310	CDD:290200	6/36 (17%)
		C2H2 Zn finger	301..321	CDD:275368	3/19 (16%)
let-391	NP_491744.3	C2H2 Zn finger	59..79	CDD:275368	5/19 (26%)
		zf-H2C2_2	73..96	CDD:290200	12/22 (55%)
		C2H2 Zn finger	87..108	CDD:275368	6/20 (30%)
		C2H2 Zn finger	116..137	CDD:275368	6/20 (30%)
		C2H2 Zn finger	270..290	CDD:275368
		zf-H2C2_2	286..304	CDD:290200
		C2H2 Zn finger	298..319	CDD:275368
		C2H2 Zn finger	327..347	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000