DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and si:ch73-158p21.7

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_017211340.1	Gene:	si:ch73-158p21.7 / 100331388	ZFINID:	ZDB-GENE-161017-32	Length:	421	Species:	Danio rerio

Alignment Length:	210	Identity:	70/210 - (33%)
Similarity:	109/210 - (51%)	Gaps:	26/210 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 EAGKTPETSEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDN 182
            ||.||.:|        .:||:  .:|:.|:..:|...|   .|..:..|...:.::::..|..::
Zfish     9 EAVKTEKT--------FRVKH--EDPEEITDLMPWKEE---IQEANDVKREKDLTEKQFISGEES 60

  Fly   183 DSWSPDSELEHEDDDKIWNASKRGKPKRVPGPY-RCKLCTQSFTQKQNLEIHMRIHTGERPYKCS 246
            ...||..:           :|:.|:|..|...| .|:.|.:.||.||.|.:||::||.|:.:.|.
Zfish    61 FRCSPTQK-----------SSQNGEPNAVDATYFTCQQCGKGFTTKQKLGVHMKVHTEEKSFTCQ 114

  Fly   247 LCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQL 311
            .|.:||.:.|.|::|.|.||||:|:.||.|.|.|:....|..|.:.||||:||.|..|.:||.:.
Zfish   115 ECGKSFNRTGKLKNHMRVHTGEKPYTCPQCGKAFKHKLTLNDHMKVHTGEKPFACQDCGKSFIKK 179

  Fly   312 NGLQKHMSAHTRGKR 326
            :.|..||..|| |:|
Zfish   180 DHLNSHMRIHT-GER 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071
		zf-C2H2	215..237	CDD:278523	10/22 (45%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		zf-H2C2_2	229..254	CDD:290200	10/24 (42%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
si:ch73-158p21.7	XP_017211340.1	COG5048	64..>386	CDD:227381	56/142 (39%)
		C2H2 Zn finger	85..105	CDD:275368	9/19 (47%)
		C2H2 Zn finger	113..133	CDD:275368	8/19 (42%)
		zf-H2C2_2	126..150	CDD:290200	13/23 (57%)
		C2H2 Zn finger	141..161	CDD:275368	7/19 (37%)
		zf-H2C2_2	154..176	CDD:290200	10/21 (48%)
		C2H2 Zn finger	169..189	CDD:275368	7/19 (37%)
		zf-H2C2_2	181..206	CDD:290200	7/14 (50%)
		C2H2 Zn finger	197..217	CDD:275368
		C2H2 Zn finger	225..245	CDD:275368
		C2H2 Zn finger	253..273	CDD:275368
		C2H2 Zn finger	281..301	CDD:275368
		C2H2 Zn finger	309..329	CDD:275368
		C2H2 Zn finger	337..357	CDD:275368
		C2H2 Zn finger	365..385	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588352
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840