DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and zgc:194336

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001124130.1	Gene:	zgc:194336 / 100170823	ZFINID:	ZDB-GENE-080723-34	Length:	496	Species:	Danio rerio

Alignment Length:	410	Identity:	98/410 - (23%)
Similarity:	151/410 - (36%)	Gaps:	116/410 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DISQMCRVCRDESDCLLDIYTE----PYASSNRVQEQEPVLATMLREC-------SGCSVH--KE 53
            |..|:....::||..|.|...|    |.|... .::.:|..:...|:|       .....|  ..
Zfish    23 DAEQITDPLKEESQDLGDFTNEERCTPTAEKT-PEKADPSSSVSCRQCGRRFGGQQSLQAHLKTH 86

  Fly    54 DGMPQFICVECAEAVRNAYRLR--------------RQCRKSHQYFEQLRLMMKELDDIEYCLNI 104
            .|...|.|..|.::......|:              .||.||.:..:.|....:
Zfish    87 SGEKPFSCDHCGKSFSKKINLKVHIRIHTGETPYTCGQCGKSFRCRDALTCHRR----------- 140

  Fly   105 GDNIEPQMPVSVMEAGKTPETSEPLLVELVQVKYMPPEPKPISSPLPDN---NEHKLAQS-YSPA 165
               |..:..|...:.||:                           .||.   ..|.|..| ..|.
Zfish   141 ---IHSERCVKCAQCGKS---------------------------FPDGTCMRNHLLVHSGEKPF 175

  Fly   166 KTPHNKSKRRARSYSDN----------------DSWSPDSELEH----EDDDKIWNASKRGK--- 207
            :....||.|.:|:...:                .|:...:.|::    ...:::::.::.||
Zfish   176 RCRCGKSFRFSRNLKTHMRIHSGERPFVCGVCGKSFCHKAGLKNHSRIHSGERLFSCAECGKSFA 240

  Fly   208 -----------PKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSH 261
                       ..|...|:.|:.|.:||:||.||:.|||||:||.||:|..|.:||.:|..|.:|
Zfish   241 YKATLSAHESAAHRGESPHACRHCGKSFSQKGNLKTHMRIHSGEMPYECVQCGKSFRRKETLNTH 305

  Fly   262 TRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTR--- 323
            ...|||:.|..|..|.|.|.:.|.|:.|.|.|:||:||.|:.|.|||.:...|..||..|:.
Zfish   306 AHTHTGDSPHTCKLCGKSFSRKGNLKTHMRIHSGERPFICAHCGQSFGRKETLNYHMKTHSSEDR 370

  Fly   324 ------GKRRTSSQETKRNK 337
                  ||.....::.||:|
Zfish   371 FICQHCGKSFPDKEQQKRHK 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	20/108 (19%)
		zf-C2H2	215..237	CDD:278523	11/21 (52%)
		C2H2 Zn finger	217..237	CDD:275368	11/19 (58%)
		zf-H2C2_2	229..254	CDD:290200	15/24 (63%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	13/23 (57%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
zgc:194336	NP_001124130.1	COG5048	65..487	CDD:227381	88/367 (24%)
		C2H2 Zn finger	66..86	CDD:275368	3/19 (16%)
		zf-H2C2_2	78..102	CDD:290200	5/23 (22%)
		C2H2 Zn finger	94..114	CDD:275368	3/19 (16%)
		zf-H2C2_2	106..131	CDD:290200	5/24 (21%)
		C2H2 Zn finger	122..142	CDD:275368	5/33 (15%)
		C2H2 Zn finger	149..169	CDD:275368	6/46 (13%)
		C2H2 Zn finger	177..196	CDD:275368	4/18 (22%)
		zf-H2C2_2	188..211	CDD:290200	0/22 (0%)
		C2H2 Zn finger	204..224	CDD:275368	2/19 (11%)
		C2H2 Zn finger	232..253	CDD:275368	2/20 (10%)
		C2H2 Zn finger	261..281	CDD:275368	11/19 (58%)
		zf-H2C2_2	273..298	CDD:290200	15/24 (63%)
		C2H2 Zn finger	289..309	CDD:275368	7/19 (37%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	8/19 (42%)
		C2H2 Zn finger	345..365	CDD:275368	8/19 (42%)
		C2H2 Zn finger	373..393	CDD:275368	5/18 (28%)
		C2H2 Zn finger	413..433	CDD:275368
		zf-H2C2_2	425..449	CDD:290200
		C2H2 Zn finger	441..461	CDD:275368
		zf-H2C2_2	453..478	CDD:290200
		C2H2 Zn finger	469..489	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000