DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17359 and znf1137

DIOPT Version :9

Sequence 1:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001103309.1	Gene:	znf1137 / 100126111	ZFINID:	ZDB-GENE-071004-87	Length:	293	Species:	Danio rerio

Alignment Length:	292	Identity:	79/292 - (27%)
Similarity:	118/292 - (40%)	Gaps:	79/292 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 KEDGMPQFICVECAEAVRNAYRLR--------------RQCRKSHQYFEQLRLMMKELDDIEYCL 102
            |..|..:|.|.:|.::......|:              .||.||........|.|:        :
Zfish    59 KRRGKNRFTCTQCGKSFGRKDILKIHMMIHTGEKPFTCTQCGKSFSLSWSRNLHMR--------I 115

  Fly   103 NIGDNIEPQMPVSVMEAGKTPETSEPLLVELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKT 167
            :.|:.     |.:..:.||                                     :.|.|.::.
Zfish   116 HSGEK-----PFTCTQCGK-------------------------------------SFSLSWSRN 138

  Fly   168 PHNKSKRRARSYSDNDSWSPDSELEHEDDDKIWNASKR---GKPKRVPGPYRCKLCTQSFTQKQN 229
            .|.:.....:.::....|...|...|      :|...|   |:.     |:.|..|.:||:...:
Zfish   139 LHMRIHSGEKPFTCTQCWKSFSSSSH------FNYHMRVHTGEK-----PFTCTQCGKSFSCSSS 192

  Fly   230 LEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHT 294
            |..||||||||:|:.|:.|.:||:|..:|..|.|.||||:||.|..|.|.|.|...|..|.|.||
Zfish   193 LNQHMRIHTGEKPFTCTQCGKSFSQSSHLNHHMRIHTGEKPFTCTQCGKSFSQSSHLNHHMRIHT 257

  Fly   295 GEQPFKCSKCQQSFKQLNGLQKHMSAHTRGKR 326
            ||:||.|::|.:||.:.:.|.:||..|| ||:
Zfish   258 GEKPFTCTQCGKSFSRSSHLNQHMRIHT-GKK 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	10/49 (20%)
		zf-C2H2	215..237	CDD:278523	8/21 (38%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		zf-H2C2_2	229..254	CDD:290200	14/24 (58%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	13/23 (57%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
znf1137	NP_001103309.1	C2H2 Zn finger	68..88	CDD:275368	3/19 (16%)
		zf-H2C2_2	81..104	CDD:290200	5/22 (23%)
		C2H2 Zn finger	96..116	CDD:275368	6/27 (22%)
		zf-H2C2_2	112..132	CDD:290200	5/69 (7%)
		C2H2 Zn finger	124..144	CDD:275368	5/56 (9%)
		COG5048	<136..>292	CDD:227381	61/165 (37%)
		zf-H2C2_2	140..161	CDD:290200	2/20 (10%)
		C2H2 Zn finger	152..172	CDD:275368	5/25 (20%)
		zf-H2C2_2	164..189	CDD:290200	9/35 (26%)
		C2H2 Zn finger	180..200	CDD:275368	8/19 (42%)
		zf-H2C2_2	192..217	CDD:290200	14/24 (58%)
		C2H2 Zn finger	208..228	CDD:275368	8/19 (42%)
		zf-H2C2_2	220..245	CDD:290200	13/24 (54%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	248..273	CDD:290200	13/24 (54%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000